Complete karyotype characterization of the K562 cell line by combined application of G-banding, multiplex-fluorescence in situ hybridization, fluorescence in situ hybridization, and comparative genomic hybridization

This study combines conventional cytogenetics, fluorescence in situ hybridization (FISH), multiplex-FISH and comparative genomic hybridization (CGH). In applying this multimodal approach on the human leukemia cell line K562, the chromosome composition was refined in detail and compared with data fro...

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Veröffentlicht in:	Leukemia research 2001-04, Vol.25 (4), p.313-322
Hauptverfasser:	Naumann, Sabine, Reutzel, Dirk, Speicher, Michael, Decker, Hans-Jochen
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences CGH Chromosome Mapping - methods Chromosome Painting - methods CML Cytogenetics - methods Genetic Markers - genetics Hematology Humans In Situ Hybridization, Fluorescence - methods Investigative techniques, diagnostic techniques (general aspects) K562 K562 Cells - metabolism K562 Cells - pathology K562 Cells - ultrastructure Karyotyping - methods M-FISH Medical sciences Nucleic Acid Hybridization - methods Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
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