Insulinotropic activity in the serum of obese and nonobese infants and children

The ability of a serum fraction, mol wt 1000-5000, to stimulate insulin release in vitro was studied in 123 obese and normal weight children aged 0-17 yr. The sera were fractionated by serial molecular filtration after treatment with urea. Stimulation of insulin release was determined with a bioassa...

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Veröffentlicht in:Pediatric research 1986-08, Vol.20 (8), p.720-723
Hauptverfasser: LAUTALA, P, AKERBLOM, H. K, KOUVALAINEN, K, MARTIN, J. M
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Sprache:eng
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