Gene expression profiling of human stent-induced neointima by cDNA array analysis of microscopic specimens retrieved by helix cutter atherectomy : Detection of FK506-binding protein 12 upregulation

Restenosis due to neointima formation is the major limitation of stent-supported balloon angioplasty. Despite abundant animal data, molecular mechanisms of neointima formation have been investigated on only a limited basis in patients. This study sought to establish a method for profiling gene expre...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2001-03, Vol.103 (10), p.1396-1402
Hauptverfasser:	ZOHLNHÖFER, Dietlind, KLEIN, Christoph A, RICHTER, Thomas, BRANDL, Richard, MURR, Alexander, NÜHRENBERG, Thomas, SCHÖMIG, Albert, BAEUERLE, Patrick A, NEUMANN, Franz-Josef
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atherectomy, Coronary Biological and medical sciences Constriction, Pathologic - etiology Constriction, Pathologic - genetics Constriction, Pathologic - metabolism Constriction, Pathologic - pathology Diseases of the cardiovascular system Female Gene Expression Profiling Humans Male Medical sciences Middle Aged Oligonucleotide Array Sequence Analysis Polymerase Chain Reaction Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Recurrence Reproducibility of Results Stents - adverse effects Tacrolimus Binding Protein 1A - genetics Tunica Intima - pathology Tunica Media - pathology Up-Regulation
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