Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies

Sixteen isoimmunized pregnancies at risk for erythroblastosis fetalis were managed by serial amniocenteses for bilirubin delta optical density at 450 nm (ΔOD450). Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vei...

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Veröffentlicht in:Obstetrics and gynecology (New York. 1953) 1986-08, Vol.68 (2), p.162-167
Hauptverfasser: VINTZILEOS, ANTHONY M, CAMPBELL, WINSTON A, STORLAZZI, EVELINA, MIROCHNICK, MARK H, ESCOTO, DANILO T, NOCHIMSON, DAVID J
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container_title Obstetrics and gynecology (New York. 1953)
container_volume 68
creator VINTZILEOS, ANTHONY M
CAMPBELL, WINSTON A
STORLAZZI, EVELINA
MIROCHNICK, MARK H
ESCOTO, DANILO T
NOCHIMSON, DAVID J
description Sixteen isoimmunized pregnancies at risk for erythroblastosis fetalis were managed by serial amniocenteses for bilirubin delta optical density at 450 nm (ΔOD450). Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vein diameter, in both the fetal liver and the umbilical cord, were measured. The ultrasonically determined fetal liver size, as well as its growth rate, was found to be greater than normal during the last two weeks before intervention (intrauterine transfusion or delivery) in all eight fetuses with severe hemolytic disease. The umbilical vein diameter in the fetal liver was above normal in only one fetus, whereas the abdominal circumference was increased in only three of the eight severely affected fetuses. These data suggest that serial fetal liver ultrasound measurements may be useful as an adjunct to amniotic fluid analysis to predict the severely affected fetus in need of prompt intervention (intrauterine transfusion or delivery).
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These data suggest that serial fetal liver ultrasound measurements may be useful as an adjunct to amniotic fluid analysis to predict the severely affected fetus in need of prompt intervention (intrauterine transfusion or delivery).</description><subject>Amniotic Fluid - immunology</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion, Intrauterine</subject><subject>Erythroblastosis, Fetal - pathology</subject><subject>Erythroblastosis, Fetal - prevention &amp; control</subject><subject>Exchange Transfusion, Whole Blood</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Liver - embryology</subject><subject>Liver - pathology</subject><subject>Management. Prenatal diagnosis</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. 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Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vein diameter, in both the fetal liver and the umbilical cord, were measured. The ultrasonically determined fetal liver size, as well as its growth rate, was found to be greater than normal during the last two weeks before intervention (intrauterine transfusion or delivery) in all eight fetuses with severe hemolytic disease. The umbilical vein diameter in the fetal liver was above normal in only one fetus, whereas the abdominal circumference was increased in only three of the eight severely affected fetuses. 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subjects Amniotic Fluid - immunology
Biological and medical sciences
Blood Transfusion, Intrauterine
Erythroblastosis, Fetal - pathology
Erythroblastosis, Fetal - prevention & control
Exchange Transfusion, Whole Blood
Female
Gestational Age
Gynecology. Andrology. Obstetrics
Humans
Infant, Newborn
Liver - embryology
Liver - pathology
Management. Prenatal diagnosis
Medical sciences
Pregnancy
Pregnancy. Fetus. Placenta
Rh Isoimmunization - pathology
Risk
Ultrasonography
Umbilical Veins - pathology
title Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies
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