Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies
Sixteen isoimmunized pregnancies at risk for erythroblastosis fetalis were managed by serial amniocenteses for bilirubin delta optical density at 450 nm (ΔOD450). Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vei...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1986-08, Vol.68 (2), p.162-167 |
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container_title | Obstetrics and gynecology (New York. 1953) |
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creator | VINTZILEOS, ANTHONY M CAMPBELL, WINSTON A STORLAZZI, EVELINA MIROCHNICK, MARK H ESCOTO, DANILO T NOCHIMSON, DAVID J |
description | Sixteen isoimmunized pregnancies at risk for erythroblastosis fetalis were managed by serial amniocenteses for bilirubin delta optical density at 450 nm (ΔOD450). Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vein diameter, in both the fetal liver and the umbilical cord, were measured. The ultrasonically determined fetal liver size, as well as its growth rate, was found to be greater than normal during the last two weeks before intervention (intrauterine transfusion or delivery) in all eight fetuses with severe hemolytic disease. The umbilical vein diameter in the fetal liver was above normal in only one fetus, whereas the abdominal circumference was increased in only three of the eight severely affected fetuses. These data suggest that serial fetal liver ultrasound measurements may be useful as an adjunct to amniotic fluid analysis to predict the severely affected fetus in need of prompt intervention (intrauterine transfusion or delivery). |
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Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vein diameter, in both the fetal liver and the umbilical cord, were measured. The ultrasonically determined fetal liver size, as well as its growth rate, was found to be greater than normal during the last two weeks before intervention (intrauterine transfusion or delivery) in all eight fetuses with severe hemolytic disease. The umbilical vein diameter in the fetal liver was above normal in only one fetus, whereas the abdominal circumference was increased in only three of the eight severely affected fetuses. These data suggest that serial fetal liver ultrasound measurements may be useful as an adjunct to amniotic fluid analysis to predict the severely affected fetus in need of prompt intervention (intrauterine transfusion or delivery).</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 3090490</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Amniotic Fluid - immunology ; Biological and medical sciences ; Blood Transfusion, Intrauterine ; Erythroblastosis, Fetal - pathology ; Erythroblastosis, Fetal - prevention & control ; Exchange Transfusion, Whole Blood ; Female ; Gestational Age ; Gynecology. Andrology. Obstetrics ; Humans ; Infant, Newborn ; Liver - embryology ; Liver - pathology ; Management. Prenatal diagnosis ; Medical sciences ; Pregnancy ; Pregnancy. Fetus. Placenta ; Rh Isoimmunization - pathology ; Risk ; Ultrasonography ; Umbilical Veins - pathology</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1986-08, Vol.68 (2), p.162-167</ispartof><rights>1986 The American College of Obstetricians and Gynecologists</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8795070$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3090490$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VINTZILEOS, ANTHONY M</creatorcontrib><creatorcontrib>CAMPBELL, WINSTON A</creatorcontrib><creatorcontrib>STORLAZZI, EVELINA</creatorcontrib><creatorcontrib>MIROCHNICK, MARK H</creatorcontrib><creatorcontrib>ESCOTO, DANILO T</creatorcontrib><creatorcontrib>NOCHIMSON, DAVID J</creatorcontrib><title>Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>Sixteen isoimmunized pregnancies at risk for erythroblastosis fetalis were managed by serial amniocenteses for bilirubin delta optical density at 450 nm (ΔOD450). Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vein diameter, in both the fetal liver and the umbilical cord, were measured. The ultrasonically determined fetal liver size, as well as its growth rate, was found to be greater than normal during the last two weeks before intervention (intrauterine transfusion or delivery) in all eight fetuses with severe hemolytic disease. The umbilical vein diameter in the fetal liver was above normal in only one fetus, whereas the abdominal circumference was increased in only three of the eight severely affected fetuses. These data suggest that serial fetal liver ultrasound measurements may be useful as an adjunct to amniotic fluid analysis to predict the severely affected fetus in need of prompt intervention (intrauterine transfusion or delivery).</description><subject>Amniotic Fluid - immunology</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion, Intrauterine</subject><subject>Erythroblastosis, Fetal - pathology</subject><subject>Erythroblastosis, Fetal - prevention & control</subject><subject>Exchange Transfusion, Whole Blood</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Liver - embryology</subject><subject>Liver - pathology</subject><subject>Management. Prenatal diagnosis</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Rh Isoimmunization - pathology</subject><subject>Risk</subject><subject>Ultrasonography</subject><subject>Umbilical Veins - pathology</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1Lw0AQhhdRaq3-BCEH8RaY_ch-nESKH4WKHix4C5vs1EY3Sd1NLPrrTWnwNMy8DwPPe0SmVCueMs7fjskUgJlUaSFOyVmMHwBApeETMuFgQBiYkpt77KxPltU3hmTlu2Bj2zcueUIb-4A1Nl1MqiZZxLaq676pftElLwHfG9uUFcZzcrK2PuLFOGdkdX_3On9Ml88Pi_ntMt0yDSJVgKpk1klKizUvHadMyUxqo5wQhRJOOcdlJtAxhjSTXMqCllobYyQFWvIZuT783Yb2q8fY5XUVS_TeNtj2MVfSyMGTDeDlCPZFjS7fhqq24ScfjYf8asxtLK1fh71H_Me0MhmoPSYO2K71HYb46fsdhnyD1nebfCgSJMsgpUZL0MOW7k-C_wFXtW4k</recordid><startdate>198608</startdate><enddate>198608</enddate><creator>VINTZILEOS, ANTHONY M</creator><creator>CAMPBELL, WINSTON A</creator><creator>STORLAZZI, EVELINA</creator><creator>MIROCHNICK, MARK H</creator><creator>ESCOTO, DANILO T</creator><creator>NOCHIMSON, DAVID J</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198608</creationdate><title>Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies</title><author>VINTZILEOS, ANTHONY M ; CAMPBELL, WINSTON A ; STORLAZZI, EVELINA ; MIROCHNICK, MARK H ; ESCOTO, DANILO T ; NOCHIMSON, DAVID J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2804-70e7c2ad611bf3cd3127656897d44b74d7dd3654ed22e156366b1c889996101c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Amniotic Fluid - immunology</topic><topic>Biological and medical sciences</topic><topic>Blood Transfusion, Intrauterine</topic><topic>Erythroblastosis, Fetal - pathology</topic><topic>Erythroblastosis, Fetal - prevention & control</topic><topic>Exchange Transfusion, Whole Blood</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Liver - embryology</topic><topic>Liver - pathology</topic><topic>Management. Prenatal diagnosis</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Rh Isoimmunization - pathology</topic><topic>Risk</topic><topic>Ultrasonography</topic><topic>Umbilical Veins - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VINTZILEOS, ANTHONY M</creatorcontrib><creatorcontrib>CAMPBELL, WINSTON A</creatorcontrib><creatorcontrib>STORLAZZI, EVELINA</creatorcontrib><creatorcontrib>MIROCHNICK, MARK H</creatorcontrib><creatorcontrib>ESCOTO, DANILO T</creatorcontrib><creatorcontrib>NOCHIMSON, DAVID J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VINTZILEOS, ANTHONY M</au><au>CAMPBELL, WINSTON A</au><au>STORLAZZI, EVELINA</au><au>MIROCHNICK, MARK H</au><au>ESCOTO, DANILO T</au><au>NOCHIMSON, DAVID J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1986-08</date><risdate>1986</risdate><volume>68</volume><issue>2</issue><spage>162</spage><epage>167</epage><pages>162-167</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>Sixteen isoimmunized pregnancies at risk for erythroblastosis fetalis were managed by serial amniocenteses for bilirubin delta optical density at 450 nm (ΔOD450). Before amniocentesis each fetus was evaluated ultrasonically and the fetal liver size, the abdominal circumference, and the umbilical vein diameter, in both the fetal liver and the umbilical cord, were measured. The ultrasonically determined fetal liver size, as well as its growth rate, was found to be greater than normal during the last two weeks before intervention (intrauterine transfusion or delivery) in all eight fetuses with severe hemolytic disease. The umbilical vein diameter in the fetal liver was above normal in only one fetus, whereas the abdominal circumference was increased in only three of the eight severely affected fetuses. These data suggest that serial fetal liver ultrasound measurements may be useful as an adjunct to amniotic fluid analysis to predict the severely affected fetus in need of prompt intervention (intrauterine transfusion or delivery).</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>3090490</pmid><tpages>6</tpages></addata></record> |
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subjects | Amniotic Fluid - immunology Biological and medical sciences Blood Transfusion, Intrauterine Erythroblastosis, Fetal - pathology Erythroblastosis, Fetal - prevention & control Exchange Transfusion, Whole Blood Female Gestational Age Gynecology. Andrology. Obstetrics Humans Infant, Newborn Liver - embryology Liver - pathology Management. Prenatal diagnosis Medical sciences Pregnancy Pregnancy. Fetus. Placenta Rh Isoimmunization - pathology Risk Ultrasonography Umbilical Veins - pathology |
title | Fetal Liver Ultrasound Measurements in Isoimmunized Pregnancies |
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