Response to a hepatitis b polypeptide vaccine in micelle form in a young adult population

Polypeptide micelles with relative molecular weights of 25,000 (p25) and 30,000 (gp30) daltons were prepared from native 22‐nm hepatitis B surface antigen (HBsAg) particles. This p25/gp30 complex was alum‐adsorbed, and three dosage levels (20 m̈g, 4 m̈g, and 0.8 m̈g) were administered at 0, 1, and 6...

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