The Determination of Draining Lymph Node Cell Cytokine mRNA Levels in BALB/c Mice Following Dermal Sodium Lauryl Sulfate, Dinitrofluorobenzene, and Toluene Diisocyanate Exposure

Differential modulation has been demonstrated in interleukin-4 (IL-4), IL-10, and interferon gamma (IFN-γ) mRNA and protein secretion patterns of cells isolated from the draining lymph nodes of mice following exposure to T cell and respiratory sensitizers. Using a multiprobe ribonuclease protection...

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Veröffentlicht in:	Toxicology and applied pharmacology 2001-03, Vol.171 (3), p.174-183
Hauptverfasser:	Manetz, T.Scott, Pettit, Denise A, Meade, B.Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	1-fluoro-2,4-dinitrobenzene Administration, Topical Animals Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases cytokine Cytokines - biosynthesis Densitometry Dinitrofluorobenzene - administration & dosage Dinitrofluorobenzene - pharmacology Female hypersensitivity IgE interleukin Lymph Nodes - cytology Lymph Nodes - drug effects Lymph Nodes - metabolism Medical sciences Mice Mice, Inbred BALB C Nuclease Protection Assays ribonuclease protection assay RNA, Messenger - biosynthesis Sodium Dodecyl Sulfate - administration & dosage Sodium Dodecyl Sulfate - pharmacology Surface-Active Agents - administration & dosage Surface-Active Agents - pharmacology T-Lymphocytes - drug effects T-Lymphocytes - metabolism Toluene 2,4-Diisocyanate - administration & dosage Toluene 2,4-Diisocyanate - pharmacology toluene diisocyanate Toxicology Various organic compounds
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