Novel synthetic analogue of ACTH 4–10 (Semax) but not glycine prevents the enhanced nitric oxide generation in cerebral cortex of rats with incomplete global ischemia

This work investigates whether nitric oxide production and lipid peroxidation contribute to the pathophysiology of ischemia and whether glycine and a novel Russian compound, Semax are neuroprotective via a mechanism involving the regulation nitric oxide (NO) and lipid peroxidation. In brief, nitric...

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Veröffentlicht in:Brain research 2001-03, Vol.894 (1), p.145-149
Hauptverfasser: Bashkatova, Valentina G, Koshelev, Vladimir B, Fadyukova, Olga E, Alexeev, Alexandr A, Vanin, Anatolii F, Rayevsky, Kirill S, Ashmarin, Igor P, Armstrong, David M
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Sprache:eng
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