Structure refinement of oligonucleotides by molecular dynamics with nuclear overhauser effect interproton distance restraints: Application to 5′ d(C-G-T-A-C-G) 2

The solution structure of the self-complementary DNA hexamer 5′ d(C-G-T-A-C-G) 2 is refined by restrained molecular dynamics in which 192 interproton distances, determined from pre-steady-state nuclear Overhauser enhancement measurements, are incorporated into the total energy of the system in the f...

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Veröffentlicht in:	Journal of molecular biology 1986-04, Vol.188 (3), p.455-475
Hauptverfasser:	Nilsson, Lennart, Clore, G.Marius, Gronenborn, Angela M., Brünger, Axel T., Karplus, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences DNA Fundamental and applied biological sciences. Psychology Magnetic Resonance Spectroscopy Models, Molecular Molecular biophysics Molecular Conformation Nucleic Acid Conformation Oligodeoxyribonucleotides Protons Structure in molecular biology Time Factors Tridimensional structure
Online-Zugang:	Volltext
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