Complete inhibition of in vivo glioma growth by oncostatin M

We describe here the oncostatin M (OSM)‐dependent inhibition of in vivo tumour formation after intracerebral inoculation of glioblastoma cells in mice. We generated human glioblastoma cells transfected with the OSM gene under the control of a tetracycline‐response promoter. Upon removal of tetracycl...

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Veröffentlicht in:	Journal of neurochemistry 2001-03, Vol.76 (5), p.1589-1592
Hauptverfasser:	Friedrich, Matthias, Höss, Norbert, Stögbauer, Florian, Senner, Volker, Paulus, Werner, Ringelstein, E. bernd, Halfter, Hartmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents - pharmacology antitumorigenic Biological and medical sciences Brain Neoplasms - pathology Cell Division - drug effects Chemotherapy Female glioblastoma glioblastoma cells Glioma - pathology Humans in vivo Medical sciences Mice Mice, Nude Oncostatin M Peptides - genetics Peptides - physiology Pharmacology. Drug treatments Promoter Regions, Genetic Recombinant Proteins - metabolism Tetracycline - pharmacology tetracycline‐inducible expression Transfection Transplantation, Heterologous Tumor Cells, Cultured
Online-Zugang:	Volltext
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