Evidence for the role of ammonia in the intracerebral transfer and metabolism of tryptophan

After portacaval shunt in the rat, the transport of tryptophan and other neutral amino acids across the blood‐brain barrier is enhanced. To determine the role of NH3 in the intracerebral transfer of tryptophan and serotonin metabolism, solutions containing either saline or NH3 or tryptophan or NH3 +...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1986-07, Vol.6 (4), p.682-686
Hauptverfasser:	Grippon, Patrick, le Poncin Lafitte, Monique, Boschat, Michèle, Wang, Shwen, Faure, Grazyna, Dutertre, Dominique, Opolon, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Ammonia - pharmacology Animals Biological and medical sciences Biological Transport - drug effects Blood-Brain Barrier - drug effects Gastroenterology. Liver. Pancreas. Abdomen Glutamine - metabolism Hydrogen-Ion Concentration Hydroxyindoleacetic Acid - metabolism Hypothalamus - blood supply Hypothalamus - metabolism Ischemia - metabolism Liver - blood supply Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Other diseases. Semiology Rats Rats, Inbred Strains Regional Blood Flow Serotonin - metabolism Tryptophan - metabolism
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