Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines

Estrogen responsiveness of breast tumors can be correlated with the presence or absence of the estrogen receptor (ER). Breast cancer cells that contain ER are, in general, responsive to stimulation by estrogen both in vivo and in vitro; therefore hormonal control is possible. Breast tumors that lose...

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Veröffentlicht in:	Journal of Steroid Biochemistry and Molecular Biology 1994-12, Vol.51 (5-6), p.229-239
Hauptverfasser:	Levenson, Anait S., Jordan, V.Craig
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biological and medical sciences Cell Division - physiology Cell Line Cell receptors Cell structures and functions DNA, Complementary Estrogens - physiology Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Humans Molecular and cellular biology Molecular Sequence Data Mutation Receptors, Estrogen - genetics Receptors, Estrogen - physiology Transfection
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