Emergence of multi-drug resistance among beta-lactamase producing salmonella

Multi-drug resistant strains of Salmonella isolated from blood and bone marrow cultures of pyrexial patients received from physicians, hospitals and different clinics were studied from May to November, 1993. Of 2143 samples collected, 424(20%) cases yielded the growth of different organisms. Out of...

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Veröffentlicht in:	Journal of the Pakistan Medical Association 1994-11, Vol.44 (11), p.253-255
Hauptverfasser:	Rehman, N, Ahmed, S I
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Quinolones Anti-Infective Agents - pharmacology Bacteremia - microbiology Bacterial diseases Bacterial diseases of the digestive system and abdomen beta-Lactamases - metabolism Biological and medical sciences Bone Marrow - microbiology Cephalosporin Resistance Chloramphenicol Resistance Drug Resistance, Microbial Drug Resistance, Multiple Fosfomycin - pharmacology Human bacterial diseases Humans Infectious diseases Medical sciences Penicillin Resistance Salmonella paratyphi A - drug effects Salmonella paratyphi A - enzymology Salmonella paratyphi A - isolation & purification Salmonella paratyphi A - physiology Salmonella typhi - drug effects Salmonella typhi - enzymology Salmonella typhi - isolation & purification Salmonella typhi - physiology Trimethoprim Resistance Trimethoprim, Sulfamethoxazole Drug Combination - pharmacology Tropical medicine Typhoid Fever - microbiology
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Zusammenfassung:	Multi-drug resistant strains of Salmonella isolated from blood and bone marrow cultures of pyrexial patients received from physicians, hospitals and different clinics were studied from May to November, 1993. Of 2143 samples collected, 424(20%) cases yielded the growth of different organisms. Out of these 266(63%) were positive for Salmonella strains. The strains isolated were Salmonella typhi 239(90%) and Salmonella paratyphi A 27(10%). Two hundred twenty (82%) strains of Salmonella showed increased beta-lactamase activity and an alarming increase in resistance against commonly used antibiotics for enteric fever.
ISSN:	0030-9982