Modes of binding and internalization of monoclonal antibodies to human melanoma cell lines

The process of monoclonal antibody (MAb) binding to tumor cells is greatly influenced by the biology of the respective antigen. This was concluded from an analysis of binding and release of MAbs and MAb fragments to melanoma cells at different concentration levels and different temperatures. With an...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1986-08, Vol.46 (8), p.3848-3854
Hauptverfasser:	MATZKU, S, BRÖCKER, E.-B, BRÜGGEN, J, DIPPOLD, W. G, TILGEN, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology Antigen-Antibody Complex - metabolism Antigens - immunology Biological and medical sciences Cell Line Dermatology Humans Hydrogen-Ion Concentration Medical sciences Melanoma - immunology Temperature Tumors of the skin and soft tissue. Premalignant lesions
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