Invasiveness and metastatic capability of rat fibroblast-like cells before and after transfection with immortalizing and transforming genes

Invasion in vitro and in vivo and spontaneous metastasis was investigated in cell lines before and after introduction of immortalizing (polyoma large-T and activated myc) genes and of transforming (polyoma middle-T and activated ras) genes in Fischer rat cells. Invasion in vitro was tested by confro...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 1986-09, Vol.46 (9), p.4787-4795
Hauptverfasser: VAN ROY, F. M, MESSIAEN, L, LIEBAUT, G, GAO, J, DRAGONETTI, C. H, FIERS, W. C, MAREEL, M. M
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Sprache:eng
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