Enzymatic and chemical probing of an S1 nuclease-sensitive site upstream from the human CFTR gene

Similar purine/pyrimidine mirror repeat ( PMR) DNA sequences have been identified in the 5'-flanking regions of the human cystic fibrosis transmembrane conductance regulator (h CFTR) and mucin (h MUC1) genes, and supercoiled (but not linearized) plasmids containing these promoter regions were p...

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Veröffentlicht in:	Gene 1994-12, Vol.150 (2), p.267-274
Hauptverfasser:	McDonald, Claudia D., Hollingsworth, Michael A., Maher, L.James
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding Sites Chloride Channels - genetics cystic fibrosis Cystic Fibrosis - genetics Cystic Fibrosis Transmembrane Conductance Regulator DNA - chemistry DNA - genetics DNA mirror repeats DNA Primers DNA, Superhelical H-DNA Hominidae - genetics homopurine DNA Humans Membrane Glycoproteins - genetics Membrane Proteins - biosynthesis Membrane Proteins - genetics Molecular Sequence Data Mucin-1 Mucins - genetics non-B-DNA Nucleic Acid Conformation Plasmids PMR Promoter Regions, Genetic Regulatory Sequences, Nucleic Acid Single-Strand Specific DNA and RNA Endonucleases
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