Evaluation of proviral copy number and plasma RNA level as early indicators of progression in HIV-1 infection: correlation with virological and immunological markers of disease

We compared the proviral DNA level in peripheral blood mononuclear cells (PBMC), viral RNA level in plasma, presence of p24 antigen in serum, viral phenotype, and results of immunological markers of HIV-1 disease. Consecutive samples of 62 HIV-1-infected patients, representing all stages of disease...

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Veröffentlicht in:	AIDS (London) 1994-10, Vol.8 (10), p.1421-1427
Hauptverfasser:	Verhofstede, C, Reniers, S, Van Wanzeele, F, Plum, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - blood Acquired Immunodeficiency Syndrome - immunology Acquired Immunodeficiency Syndrome - virology AIDS/HIV Base Sequence CD4 Lymphocyte Count DNA Primers DNA, Viral - analysis DNA, Viral - blood HIV Reverse Transcriptase HIV-1 - classification HIV-1 - genetics HIV-1 - isolation & purification human immunodeficiency virus 1 Humans Molecular Sequence Data Phenotype Polymerase Chain Reaction Predictive Value of Tests Prognosis Proviruses - genetics Proviruses - isolation & purification RNA, Viral - blood RNA-Directed DNA Polymerase - genetics
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