Exogenous CoQ10 preserves plasma ubiquinone levels in patients treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

Ubiquinone is a carrier of the mitochondrial respiratory chain which regulates oxidative phosphorylation: it also acts as a membrane stabilizer preventing lipid peroxidation. In man the quinone ring originates from tyrosine, while the formation of the polyisoprenoid lateral chain starts from acetyl...

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Veröffentlicht in:	International journal of clinical & laboratory research 1994-09, Vol.24 (3), p.171-176
Hauptverfasser:	Bargossi, A M, Battino, M, Gaddi, A, Fiorella, P L, Grossi, G, Barozzi, G, Di Giulio, R, Descovich, G, Sassi, S, Genova, M L
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Anticholesteremic Agents - pharmacology Blood Platelets - drug effects Blood Platelets - metabolism Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Lovastatin - analogs & derivatives Lovastatin - pharmacology Male Simvastatin Ubiquinone - blood Ubiquinone - pharmacology
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