Altered Regulation of Airway Epithelial Cell Chloride Channels in Cystic Fibrosis

In many epithelial cells the chloride conductance of the apical membrane increases during the stimulation of electrolyte secretion. Single-channel recordings from human airway epithelial cells showed that $\beta $-adrenergic stimulation evoked apical membrane chloride channel activity, but this resp...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1986-08, Vol.233 (4763), p.558-560
Hauptverfasser:	Frizzell, Raymond A., Rechkemmer, Gerhard, Shoemaker, Richard L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and medical sciences Butchering Calcium - pharmacology Cell culture techniques chloride Chloride cells Chloride channels Chlorides - metabolism Cyclic AMP - pharmacology Cystic fibrosis Cystic Fibrosis - metabolism Cystic Fibrosis - physiopathology Cytochemistry Epinephrine - pharmacology Epithelial cells Epithelium Epithelium - metabolism Gastroenterology. Liver. Pancreas. Abdomen Hepatitis E virus Humans Ion Channels - drug effects Ion Channels - physiology Liver. Biliary tract. Portal circulation. Exocrine pancreas Lymphocytes man Medical research Medical sciences Membrane Potentials - drug effects Other diseases. Semiology Physiological regulation Pipettes Respiratory System - metabolism Respiratory System - physiopathology respiratory tract Secretion
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