Comment on the Interpretation of Effects Caused by Chronic Trichloroethylene Exposure
Work was started with the intention of testing effects on the central nervous system from exposure to trichloroethylene. In the experiments the authors used a symetrical labyrinth as a probe for spatial memory. This behavior is extremely sensitive to damage in the hippocampal area, while other parts...
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| Veröffentlicht in: | Scandinavian Journal of Work, Environment ＆ Health Environment ＆ Health, 1986-04, Vol.12 (2), p.154-155 |
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| container_issue | 2 |
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| container_title | Scandinavian Journal of Work, Environment ＆ Health |
| container_volume | 12 |
| creator | Kjellstrand, Per |
| description | Work was started with the intention of testing effects on the central nervous system from exposure to trichloroethylene. In the experiments the authors used a symetrical labyrinth as a probe for spatial memory. This behavior is extremely sensitive to damage in the hippocampal area, while other parts of the brain seem not to be involved in any prominent way. Results were that no effects on seedseeking behavior in the labyrinth could be seen during the solvent exposure or after it had been terminated. If, however, the animals were challenged by a second exposure several months after termination of the first, significant differences between the previously exposed animals and the controls were found. The effects can be considered both as irreversible and covert. |
| doi_str_mv | 10.5271/sjweh.2163 |
| format | Article |
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| identifier | ISSN: 0355-3140 |
| ispartof | Scandinavian Journal of Work, Environment ＆ Health, 1986-04, Vol.12 (2), p.154-155 |
| issn | 0355-3140 1795-990X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76925047 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; EZB-FREE-00999 freely available EZB journals |
| subjects | Animal nesting Animals Behavior, Animal - drug effects Biochemistry Central nervous system Central Nervous System - drug effects Emotionality Gerbillinae Labyrinths Learning LETTERS TO THE EDITOR Mazes Memory Mice Solvents Time Factors Trichloroethylene - pharmacology |
| title | Comment on the Interpretation of Effects Caused by Chronic Trichloroethylene Exposure |
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