Mapping Studies of Two G Protein-Coupled Receptor Genes: An Amino Acid Difference May Confer a Functional Variation Between a Human and Rodent Receptor

We recently isolated two orphan human G protein-coupled receptor genes designated GPR1 and GPR6. The gene GPR1 was shown to be transcribed abundantly but only in the hippocampus. Here we report the cloning of the rat GPR1 gene and report the absence of expression in hippocampus, demonstrating a func...

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