The Violated Neck: Cervical Node Biopsy Prior to Definitive Treatment
The intent of this study was to determine whether open neck biopsy for patients with squamous cell carcinoma metastatic to the neck influenced the biologic course of the disease or the response to treatment. One hundred ninety-two patients, treated over a 10-year period at M.D. Anderson Hospital and...
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| Veröffentlicht in: | Otolaryngology-head and neck surgery 1986-06, Vol.94 (5), p.605-610 |
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| container_title | Otolaryngology-head and neck surgery |
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| creator | Robbins, K. Thomas Cole, Randolph Marvel, Jeffrey Fields, Robert Wolf, Patricia Goepfert, Helmuth |
| description | The intent of this study was to determine whether open neck biopsy for patients with squamous cell carcinoma metastatic to the neck influenced the biologic course of the disease or the response to treatment. One hundred ninety-two patients, treated over a 10-year period at M.D. Anderson Hospital and Tumor institute, were reviewed; 102 of the 139 patients, whose primary site of disease was identified prior to definitive treatment, were matched with a control group of 204 patients. The results showed no significant difference in wound complications, neck recurrence, distant metastases, and 5-year survival. Also, time interval from the biopsy to subsequent treatment and the type of node biopsy did not appear to have any significant detrimental effect. On the basis of these findings, we conclude that, although it is important to refrain from proceeding with an open biopsy until a complete head and neck evaluation has been done, violation of the neck does not signify a poorer prognosis—provided adequate treatment is subsequently given. |
| doi_str_mv | 10.1177/019459988609400513 |
| format | Article |
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Thomas ; Cole, Randolph ; Marvel, Jeffrey ; Fields, Robert ; Wolf, Patricia ; Goepfert, Helmuth</creator><creatorcontrib>Robbins, K. Thomas ; Cole, Randolph ; Marvel, Jeffrey ; Fields, Robert ; Wolf, Patricia ; Goepfert, Helmuth</creatorcontrib><description>The intent of this study was to determine whether open neck biopsy for patients with squamous cell carcinoma metastatic to the neck influenced the biologic course of the disease or the response to treatment. One hundred ninety-two patients, treated over a 10-year period at M.D. Anderson Hospital and Tumor institute, were reviewed; 102 of the 139 patients, whose primary site of disease was identified prior to definitive treatment, were matched with a control group of 204 patients. The results showed no significant difference in wound complications, neck recurrence, distant metastases, and 5-year survival. Also, time interval from the biopsy to subsequent treatment and the type of node biopsy did not appear to have any significant detrimental effect. On the basis of these findings, we conclude that, although it is important to refrain from proceeding with an open biopsy until a complete head and neck evaluation has been done, violation of the neck does not signify a poorer prognosis—provided adequate treatment is subsequently given.</description><identifier>ISSN: 0194-5998</identifier><identifier>EISSN: 1097-6817</identifier><identifier>DOI: 10.1177/019459988609400513</identifier><identifier>PMID: 3088524</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adolescent ; Adult ; Aged ; Biopsy - adverse effects ; Biopsy - methods ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - secondary ; Carcinoma, Squamous Cell - therapy ; Child ; Combined Modality Therapy ; Female ; Humans ; Lymph Nodes - pathology ; Lymphatic Metastasis - mortality ; Lymphatic Metastasis - pathology ; Male ; Middle Aged ; Neck ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Otorhinolaryngologic Neoplasms - mortality ; Otorhinolaryngologic Neoplasms - pathology ; Otorhinolaryngologic Neoplasms - secondary ; Otorhinolaryngologic Neoplasms - therapy</subject><ispartof>Otolaryngology-head and neck surgery, 1986-06, Vol.94 (5), p.605-610</ispartof><rights>1986 SAGE Publications</rights><rights>1986 American Association of Otolaryngology‐Head and Neck Surgery Foundation (AAO‐HNSF)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3895-34547c2b250fddcc5f141b4b1d22540fc4230d02fcce0528c64a1474eb6956813</citedby><cites>FETCH-LOGICAL-c3895-34547c2b250fddcc5f141b4b1d22540fc4230d02fcce0528c64a1474eb6956813</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1177%2F019459988609400513$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1177%2F019459988609400513$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3088524$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Robbins, K. Thomas</creatorcontrib><creatorcontrib>Cole, Randolph</creatorcontrib><creatorcontrib>Marvel, Jeffrey</creatorcontrib><creatorcontrib>Fields, Robert</creatorcontrib><creatorcontrib>Wolf, Patricia</creatorcontrib><creatorcontrib>Goepfert, Helmuth</creatorcontrib><title>The Violated Neck: Cervical Node Biopsy Prior to Definitive Treatment</title><title>Otolaryngology-head and neck surgery</title><addtitle>Otolaryngol Head Neck Surg</addtitle><description>The intent of this study was to determine whether open neck biopsy for patients with squamous cell carcinoma metastatic to the neck influenced the biologic course of the disease or the response to treatment. One hundred ninety-two patients, treated over a 10-year period at M.D. Anderson Hospital and Tumor institute, were reviewed; 102 of the 139 patients, whose primary site of disease was identified prior to definitive treatment, were matched with a control group of 204 patients. The results showed no significant difference in wound complications, neck recurrence, distant metastases, and 5-year survival. Also, time interval from the biopsy to subsequent treatment and the type of node biopsy did not appear to have any significant detrimental effect. On the basis of these findings, we conclude that, although it is important to refrain from proceeding with an open biopsy until a complete head and neck evaluation has been done, violation of the neck does not signify a poorer prognosis—provided adequate treatment is subsequently given.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biopsy - adverse effects</subject><subject>Biopsy - methods</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - secondary</subject><subject>Carcinoma, Squamous Cell - therapy</subject><subject>Child</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis - mortality</subject><subject>Lymphatic Metastasis - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neck</subject><subject>Neoplasm Recurrence, Local</subject><subject>Neoplasm Staging</subject><subject>Otorhinolaryngologic Neoplasms - mortality</subject><subject>Otorhinolaryngologic Neoplasms - pathology</subject><subject>Otorhinolaryngologic Neoplasms - secondary</subject><subject>Otorhinolaryngologic Neoplasms - therapy</subject><issn>0194-5998</issn><issn>1097-6817</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMFOwkAQhjdGg4i-gInJnrxVZre73ZabIIgJAQ_otWm3U10sLO4WDG9vCcSLifE0h_m_PzMfIdcM7hhTqgssETJJ4jiCRABIFp6QNoNEBVHM1Clp7wPBPnFOLrxfAEAUKdUirRDiWHLRJsP5O9JXY6usxoJOUX_06ADd1uisolNbIO0bu_Y7-uyMdbS29AFLszK12SKdO8zqJa7qS3JWZpXHq-PskJfRcD4YB5PZ49PgfhLoME5kEAoplOY5l1AWhdayZILlImcF51JAqQUPoQBeao0geawjkTGhBOZRIpuXwg65PfSunf3coK_TpfEaqypbod34VEUJB873QX4Iame9d1ima2eWmdulDNK9u_S3uwa6ObZv8iUWP8hRVrPvHfZfpsLdPxrT2XjaHwFTQjZw9wD77A3Thd24VWPqr3O-AfjZhUU</recordid><startdate>198606</startdate><enddate>198606</enddate><creator>Robbins, K. Thomas</creator><creator>Cole, Randolph</creator><creator>Marvel, Jeffrey</creator><creator>Fields, Robert</creator><creator>Wolf, Patricia</creator><creator>Goepfert, Helmuth</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>198606</creationdate><title>The Violated Neck: Cervical Node Biopsy Prior to Definitive Treatment</title><author>Robbins, K. Thomas ; Cole, Randolph ; Marvel, Jeffrey ; Fields, Robert ; Wolf, Patricia ; Goepfert, Helmuth</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3895-34547c2b250fddcc5f141b4b1d22540fc4230d02fcce0528c64a1474eb6956813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biopsy - adverse effects</topic><topic>Biopsy - methods</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - secondary</topic><topic>Carcinoma, Squamous Cell - therapy</topic><topic>Child</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis - mortality</topic><topic>Lymphatic Metastasis - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neck</topic><topic>Neoplasm Recurrence, Local</topic><topic>Neoplasm Staging</topic><topic>Otorhinolaryngologic Neoplasms - mortality</topic><topic>Otorhinolaryngologic Neoplasms - pathology</topic><topic>Otorhinolaryngologic Neoplasms - secondary</topic><topic>Otorhinolaryngologic Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Robbins, K. Thomas</creatorcontrib><creatorcontrib>Cole, Randolph</creatorcontrib><creatorcontrib>Marvel, Jeffrey</creatorcontrib><creatorcontrib>Fields, Robert</creatorcontrib><creatorcontrib>Wolf, Patricia</creatorcontrib><creatorcontrib>Goepfert, Helmuth</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Otolaryngology-head and neck surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Robbins, K. Thomas</au><au>Cole, Randolph</au><au>Marvel, Jeffrey</au><au>Fields, Robert</au><au>Wolf, Patricia</au><au>Goepfert, Helmuth</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Violated Neck: Cervical Node Biopsy Prior to Definitive Treatment</atitle><jtitle>Otolaryngology-head and neck surgery</jtitle><addtitle>Otolaryngol Head Neck Surg</addtitle><date>1986-06</date><risdate>1986</risdate><volume>94</volume><issue>5</issue><spage>605</spage><epage>610</epage><pages>605-610</pages><issn>0194-5998</issn><eissn>1097-6817</eissn><abstract>The intent of this study was to determine whether open neck biopsy for patients with squamous cell carcinoma metastatic to the neck influenced the biologic course of the disease or the response to treatment. One hundred ninety-two patients, treated over a 10-year period at M.D. Anderson Hospital and Tumor institute, were reviewed; 102 of the 139 patients, whose primary site of disease was identified prior to definitive treatment, were matched with a control group of 204 patients. The results showed no significant difference in wound complications, neck recurrence, distant metastases, and 5-year survival. Also, time interval from the biopsy to subsequent treatment and the type of node biopsy did not appear to have any significant detrimental effect. On the basis of these findings, we conclude that, although it is important to refrain from proceeding with an open biopsy until a complete head and neck evaluation has been done, violation of the neck does not signify a poorer prognosis—provided adequate treatment is subsequently given.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>3088524</pmid><doi>10.1177/019459988609400513</doi><tpages>6</tpages></addata></record> |
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| ispartof | Otolaryngology-head and neck surgery, 1986-06, Vol.94 (5), p.605-610 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Adolescent Adult Aged Biopsy - adverse effects Biopsy - methods Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - secondary Carcinoma, Squamous Cell - therapy Child Combined Modality Therapy Female Humans Lymph Nodes - pathology Lymphatic Metastasis - mortality Lymphatic Metastasis - pathology Male Middle Aged Neck Neoplasm Recurrence, Local Neoplasm Staging Otorhinolaryngologic Neoplasms - mortality Otorhinolaryngologic Neoplasms - pathology Otorhinolaryngologic Neoplasms - secondary Otorhinolaryngologic Neoplasms - therapy |
| title | The Violated Neck: Cervical Node Biopsy Prior to Definitive Treatment |
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