Stereospecific effects of d- and l-pentazocine on contractions of the mouse vas deferens

The effects of the d- and l-isomers of pentazocine were compared to that of racemic pentazocine on contractions of the mouse isolated vas deferens. L-pentazocine inhibited electrically evoked contractions of the mouse vas deferens (MVD) in a dose-dependent manner (ID 50 0.37±0.04 μM ). In contrast,...

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Veröffentlicht in:	Life sciences (1973) 1986-07, Vol.39 (2), p.127-133
Hauptverfasser:	Kinouchi, Keiko, Fukumitsu, Kazuo, Takezawa, Jun, Maeda, Sadaaki, Enomoto, Haruo, Kakuhari, Jiroh, Yoshiya, Ikuto, Inoki, Reizo
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Animals Biological and medical sciences Electric Stimulation Male Medical sciences Mice Muscle Contraction - drug effects Naloxone - pharmacology Neuropharmacology Norepinephrine - pharmacology Pentazocine - pharmacology Pharmacology. Drug treatments Receptors, Opioid - drug effects Stereoisomerism Vas Deferens - drug effects
Online-Zugang:	Volltext
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