Natural and Vaccine-Related Immunity to Streptococcus pneumoniae

To investigate the protective effects of pneumococcal vaccine, we assayed serum from healthy adults and from elderly bronchitics for antibody and opsonic activity against nine serotypes of S. pneumoniae. Before vaccination, there was no relation between opsonization and the level of antibody measure...

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Veröffentlicht in:	The Journal of infectious diseases 1986-08, Vol.154 (2), p.245-256
Hauptverfasser:	Musher, Daniel M., Chapman, Alan J., Goree, Allen, Jonsson, Steinn, Briles, David, Baughn, Robert E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alveolar macrophages Antibodies Antibodies, Bacterial - analysis Antibodies, Bacterial - immunology Bacteria Bacterial diseases Bacterial Vaccines - immunology Biological and medical sciences Bronchitis - immunology Complement Activation Human bacterial diseases Humans Infections Infectious diseases Macrophages - immunology Male Medical sciences Middle Aged Older adults Opsonin Proteins - immunology Origical Articles Phagocytosis Phosphorylcholine - immunology Pneumococcal vaccine Pneumococcal Vaccines Polysaccharides Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcus pneumoniae Streptococcus pneumoniae - immunology Vaccination
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