Different substrate specificities of the two DNA ligases of mammalian cells

Mammalian cells contain the DNA ligases I and II. These enzymes show different molecular weights and heat labilities, and antibodies against ligase I do not inhibit ligase II. Here, the nonidentical substrate specificities of the enzymes are described. Under standard reaction conditions DNA ligase I...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 1986-07, Vol.261 (20), p.9079-9082
Hauptverfasser:	Arrand, J E, Willis, A E, Goldsmith, I, Lindahl, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Cattle DNA - metabolism DNA Ligase ATP DNA Ligases - metabolism Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Hydrogen Bonding Ligases Oligodeoxyribonucleotides - metabolism Poly A - metabolism Polynucleotide Ligases - metabolism Substrate Specificity T-Phages - enzymology Thymus Gland - enzymology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!