Insulin provokes a transient activation of phospholipase C in the rat epididymal fat pad

Insulin is known to increase the de novo synthesis of inositol phospholipids in rat epididymal fat pads. We presently examined the effects of insulin on the hydrolysis of inositol phospholipids in this tissue. Relatively small (30-40%) but significant increases in inositol phosphates (mono-, di-, an...

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Veröffentlicht in:	The Journal of biological chemistry 1986-07, Vol.261 (19), p.8589-8592
Hauptverfasser:	Farese, R V, Kuo, J Y, Babischkin, J S, Davis, J S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - enzymology Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Enzyme Activation Enzymes and enzyme inhibitors Epididymis Fundamental and applied biological sciences. Psychology Hydrolases Insulin - pharmacology Kinetics Male Phosphates - metabolism Phosphatidylinositols - biosynthesis Phosphorus Radioisotopes Rats Tritium - metabolism Type C Phospholipases - metabolism
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