NEW CHLORINE-CONTAINING PRENYLATED C6-C3 COMPOUNDS INCREASING CHOLINE ACETYLTRANSFERASE (ChAT) ACTIVITY IN CULTURE OF POSTNATAL RAT SEPTAL NEURONS FROM ILLICIUM TASHIROI
The structures of two new chlorine-containing C6-C3 compounds isolated from the woods of Illicium tashiroi have been established as 2(R)-12-chloro-2, 3-dihydroillicinone E (1) and 12-chloroillicinone E (2) by X-ray crystallographic analysis and spectroscopic data, respectively. Compound 1 has been f...
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| Veröffentlicht in: | Chemical & pharmaceutical bulletin 1994/10/15, Vol.42(10), pp.2199-2201 |
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| container_title | Chemical & pharmaceutical bulletin |
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| creator | FUKUYAMA, Yoshiyasu OKAMOTO, Kazumi KUBO, Youko SHIDA, Naomi KODAMA, Mitsuaki |
| description | The structures of two new chlorine-containing C6-C3 compounds isolated from the woods of Illicium tashiroi have been established as 2(R)-12-chloro-2, 3-dihydroillicinone E (1) and 12-chloroillicinone E (2) by X-ray crystallographic analysis and spectroscopic data, respectively. Compound 1 has been found to significantly increase ChAT activity in culture of P10 rat sepatl neurons. |
| doi_str_mv | 10.1248/cpb.42.2199 |
| format | Article |
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Compound 1 has been found to significantly increase ChAT activity in culture of P10 rat sepatl neurons.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.42.2199</identifier><identifier>PMID: 7805142</identifier><language>eng</language><publisher>Japan: The Pharmaceutical Society of Japan</publisher><subject>12-chloroillicinone E ; 2(R)-12-chloro-2, 3-dihydroillicinone E ; Animals ; Benzofurans - isolation & purification ; Benzofurans - pharmacology ; Cells, Cultured ; choline acetyltransferase activity ; Choline O-Acetyltransferase - metabolism ; Dioxoles - isolation & purification ; Dioxoles - pharmacology ; Illicium tashiroi ; Magnoliaceae ; Neurons - drug effects ; Neurons - enzymology ; Plant Extracts - isolation & purification ; Plant Extracts - pharmacology ; prenylated C6-C3 compound ; Rats ; Septal Nuclei - cytology ; Structure-Activity Relationship</subject><ispartof>Chemical and Pharmaceutical Bulletin, 1994/10/15, Vol.42(10), pp.2199-2201</ispartof><rights>The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 1994</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4949-abf8283dea21330c3bb619ae3ffdb0ea9bdcfe692e5d96f1512b77631f44d39f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,1884,4025,27928,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7805142$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FUKUYAMA, Yoshiyasu</creatorcontrib><creatorcontrib>OKAMOTO, Kazumi</creatorcontrib><creatorcontrib>KUBO, Youko</creatorcontrib><creatorcontrib>SHIDA, Naomi</creatorcontrib><creatorcontrib>KODAMA, Mitsuaki</creatorcontrib><title>NEW CHLORINE-CONTAINING PRENYLATED C6-C3 COMPOUNDS INCREASING CHOLINE ACETYLTRANSFERASE (ChAT) ACTIVITY IN CULTURE OF POSTNATAL RAT SEPTAL NEURONS FROM ILLICIUM TASHIROI</title><title>Chemical & pharmaceutical bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>The structures of two new chlorine-containing C6-C3 compounds isolated from the woods of Illicium tashiroi have been established as 2(R)-12-chloro-2, 3-dihydroillicinone E (1) and 12-chloroillicinone E (2) by X-ray crystallographic analysis and spectroscopic data, respectively. Compound 1 has been found to significantly increase ChAT activity in culture of P10 rat sepatl neurons.</description><subject>12-chloroillicinone E</subject><subject>2(R)-12-chloro-2, 3-dihydroillicinone E</subject><subject>Animals</subject><subject>Benzofurans - isolation & purification</subject><subject>Benzofurans - pharmacology</subject><subject>Cells, Cultured</subject><subject>choline acetyltransferase activity</subject><subject>Choline O-Acetyltransferase - metabolism</subject><subject>Dioxoles - isolation & purification</subject><subject>Dioxoles - pharmacology</subject><subject>Illicium tashiroi</subject><subject>Magnoliaceae</subject><subject>Neurons - drug effects</subject><subject>Neurons - enzymology</subject><subject>Plant Extracts - isolation & purification</subject><subject>Plant Extracts - pharmacology</subject><subject>prenylated C6-C3 compound</subject><subject>Rats</subject><subject>Septal Nuclei - cytology</subject><subject>Structure-Activity Relationship</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkVuL1DAYhoso67h65bUQEESRjjn1kMuQTXcCnWRoU2WuSg-pO8OcbGcu_En-S1tmWMGbJPA-38NHXs97j-AcYRp_a071nOI5Roy98GaI0MgPMCYvvRmEkPmYhOS192YYthDiAEbkzruLYhggimfeHy1_ALFITaa09IXRliut9CNYZVKvU27lAxChLwgQZrkyhX7IgdIikzyfKLEw6TgIuJB2ndqM6zyRGc8l-CyeuP0yBlZ9V3Y9DgFRpLbIJDAJWJncam55CjJuQS5X01PLIjM6B0lmlkClqRKqWALL84XKjHrrveqq3eDe3e57r0ikFQs_NY9K8NRvKKPMr-ouxjFpXYURIbAhdR0iVjnSdW0NXcXqtulcyLALWhZ2KEC4jqKQoI7SlrCO3Hufrt5Tf_x1ccO53G-Gxu121cEdL0MZhWz8QxqO4Mf_wO3x0h_G3UpEQ4jjKIroSH29Uk1_HIbedeWp3-yr_neJYDnVV471lRSXU30j_eHmvNR71z6zt77GPLnm2-Fc_XTPedWfN83OTS7EgnjyjfrrOYn_AU9VX7oD-QvpG6Dl</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>FUKUYAMA, Yoshiyasu</creator><creator>OKAMOTO, Kazumi</creator><creator>KUBO, Youko</creator><creator>SHIDA, Naomi</creator><creator>KODAMA, Mitsuaki</creator><general>The Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>NEW CHLORINE-CONTAINING PRENYLATED C6-C3 COMPOUNDS INCREASING CHOLINE ACETYLTRANSFERASE (ChAT) ACTIVITY IN CULTURE OF POSTNATAL RAT SEPTAL NEURONS FROM ILLICIUM TASHIROI</title><author>FUKUYAMA, Yoshiyasu ; OKAMOTO, Kazumi ; KUBO, Youko ; SHIDA, Naomi ; KODAMA, Mitsuaki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4949-abf8283dea21330c3bb619ae3ffdb0ea9bdcfe692e5d96f1512b77631f44d39f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>12-chloroillicinone E</topic><topic>2(R)-12-chloro-2, 3-dihydroillicinone E</topic><topic>Animals</topic><topic>Benzofurans - isolation & purification</topic><topic>Benzofurans - pharmacology</topic><topic>Cells, Cultured</topic><topic>choline acetyltransferase activity</topic><topic>Choline O-Acetyltransferase - metabolism</topic><topic>Dioxoles - isolation & purification</topic><topic>Dioxoles - pharmacology</topic><topic>Illicium tashiroi</topic><topic>Magnoliaceae</topic><topic>Neurons - drug effects</topic><topic>Neurons - enzymology</topic><topic>Plant Extracts - isolation & purification</topic><topic>Plant Extracts - pharmacology</topic><topic>prenylated C6-C3 compound</topic><topic>Rats</topic><topic>Septal Nuclei - cytology</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FUKUYAMA, Yoshiyasu</creatorcontrib><creatorcontrib>OKAMOTO, Kazumi</creatorcontrib><creatorcontrib>KUBO, Youko</creatorcontrib><creatorcontrib>SHIDA, Naomi</creatorcontrib><creatorcontrib>KODAMA, Mitsuaki</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical & pharmaceutical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FUKUYAMA, Yoshiyasu</au><au>OKAMOTO, Kazumi</au><au>KUBO, Youko</au><au>SHIDA, Naomi</au><au>KODAMA, Mitsuaki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>NEW CHLORINE-CONTAINING PRENYLATED C6-C3 COMPOUNDS INCREASING CHOLINE ACETYLTRANSFERASE (ChAT) ACTIVITY IN CULTURE OF POSTNATAL RAT SEPTAL NEURONS FROM ILLICIUM TASHIROI</atitle><jtitle>Chemical & pharmaceutical bulletin</jtitle><addtitle>Chem. Pharm. Bull.</addtitle><date>1994</date><risdate>1994</risdate><volume>42</volume><issue>10</issue><spage>2199</spage><epage>2201</epage><pages>2199-2201</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><abstract>The structures of two new chlorine-containing C6-C3 compounds isolated from the woods of Illicium tashiroi have been established as 2(R)-12-chloro-2, 3-dihydroillicinone E (1) and 12-chloroillicinone E (2) by X-ray crystallographic analysis and spectroscopic data, respectively. Compound 1 has been found to significantly increase ChAT activity in culture of P10 rat sepatl neurons.</abstract><cop>Japan</cop><pub>The Pharmaceutical Society of Japan</pub><pmid>7805142</pmid><doi>10.1248/cpb.42.2199</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-2363 |
| ispartof | Chemical and Pharmaceutical Bulletin, 1994/10/15, Vol.42(10), pp.2199-2201 |
| issn | 0009-2363 1347-5223 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Free Full-Text Journals in Chemistry |
| subjects | 12-chloroillicinone E 2(R)-12-chloro-2, 3-dihydroillicinone E Animals Benzofurans - isolation & purification Benzofurans - pharmacology Cells, Cultured choline acetyltransferase activity Choline O-Acetyltransferase - metabolism Dioxoles - isolation & purification Dioxoles - pharmacology Illicium tashiroi Magnoliaceae Neurons - drug effects Neurons - enzymology Plant Extracts - isolation & purification Plant Extracts - pharmacology prenylated C6-C3 compound Rats Septal Nuclei - cytology Structure-Activity Relationship |
| title | NEW CHLORINE-CONTAINING PRENYLATED C6-C3 COMPOUNDS INCREASING CHOLINE ACETYLTRANSFERASE (ChAT) ACTIVITY IN CULTURE OF POSTNATAL RAT SEPTAL NEURONS FROM ILLICIUM TASHIROI |
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