Protection by dexamethasone from a lethal infection with Listeria monocytogenes in mice

The effects of dexamethasone (DEX) on a lethal infection with Listeria monocytogenes were studied in mice. Mice were completely protected against the lethal infection when treated with 3.3 mg per kg of DEX. The effect was observed only when DEX was injected before infection. The control mice died fr...

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Veröffentlicht in:	FEMS immunology and medical microbiology 1994-08, Vol.9 (2), p.163-170
Hauptverfasser:	Nakane, Akio, Okamoto, Munenori, Asano, Misako, Kohanawa, Masashi, Satoh, Yu‐ichiro, Minagawa, Tomonori
Format:	Artikel
Sprache:	eng
Schlagworte:	Action of physical and chemical agents on bacteria Animals Bacteriology Biological and medical sciences Dexamethasone Dexamethasone - pharmacology Female Fundamental and applied biological sciences. Psychology Gamma interferon Glucocorticoid Interferon-gamma - biosynthesis Interleukin-6 - biosynthesis Interleukin‐6 Listeria monocytogenes Listeria monocytogenes - drug effects Listeria monocytogenes - growth & development Listeriosis - metabolism Listeriosis - pathology Listeriosis - prevention & control Liver - pathology Mice Microbiology Tumor Necrosis Factor-alpha - biosynthesis Tumour necrosis factor
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