Genetic and Physical Mapping of a Gene Encoding a Methyl CpG Binding Protein, Mecp2, to the Mouse X Chromosome

The methyl CpG binding proteins (MeCP1 and MeCP2) are a class of proteins that bind to templates containing symmetrically methylated CpGs. Using an interspecific backcross segregating a number of X-linked markers, we have localized the Mecp2 gene in mouse to the X chromosome close to the microsatell...

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Veröffentlicht in:	Genomics 1994-08, Vol.22 (3), p.648-651
Hauptverfasser:	Quaderi, N.A., Meehan, R.R., Tate, P.H., Cross, S.H., Bird, A.P., Chatterjee, A., Herman, G.E., Brown, S.D.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences BIOLOGICAL MARKERS BIOLOGY AND MEDICINE, BASIC STUDIES Chromosomal Proteins, Non-Histone Chromosome Mapping Chromosomes, Artificial, Yeast Classical genetics, quantitative genetics, hybrids CONTIGS Crosses, Genetic DNA DNA Primers - genetics DNA-Binding Proteins - genetics Female Fundamental and applied biological sciences. Psychology GENES GENETIC MAPPING Genetics of eukaryotes. Biological and molecular evolution Humans HYBRIDIZATION Male Methyl-CpG-Binding Protein 2 MICE Mice, Inbred C57BL Molecular Sequence Data Muridae POLYMERASE CHAIN REACTION PROTEINS Repressor Proteins RESOLUTION Species Specificity Vertebrata X CHROMOSOME YEASTS
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