Value of Different Clinical and Biochemical Correlates to Assess Angiotensin Converting Enzyme Inhibition

SUMMARYIn a double-blind study, we compared the value of different approaches to assess blockade of angiotensin (Ang) II generation in 10 normal volunteers treated with the new Ang-converting enzyme (ACE) inhibitor temocapril. Plasma concentration of the diacid active metabolite of temocapril, plasm...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1994-09, Vol.24 (3), p.479-485
Hauptverfasser:	Delacrétaz, Etienne, Nussberger, Jürg, Püchler, Kurt, Wood, Alan J, Robinson, Philip R, Waeber, Bernard, Brunner, Hans R
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Angiotensin I - administration & dosage Angiotensin I - antagonists & inhibitors Angiotensin I - blood Angiotensin I - pharmacology Angiotensin II - blood Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - blood Angiotensin-Converting Enzyme Inhibitors - pharmacology Antihypertensive agents Biological and medical sciences Blood Pressure - drug effects Cardiovascular system Dose-Response Relationship, Drug Double-Blind Method Drug Evaluation Humans Injections, Intravenous Male Medical sciences Pharmacology. Drug treatments Reproducibility of Results Tablets Thiazepines - administration & dosage Thiazepines - blood Thiazepines - pharmacology
Online-Zugang:	Volltext
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