myo‐Inositol reverses Li+‐induced inhibition of phosphoinositide turnover and ornithine decarboxylase induction during early lymphocyte activation

One of the earliest detectable responses by T lymphocytes in vitro to various mitogenic ligands is the rapid induction of ornithine decarboxylase (ODC) activity (Scott et al., Eur. J. Immunol. 1985. 15: 783). This early activation is measurable within minutes after the addition of the mitogen. The T...

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Veröffentlicht in:	European journal of immunology 1986, Vol.16 (7), p.859-861
Hauptverfasser:	Mustelin, Tomas, Pösö, Hannu, Iivanainen, Antti, Andersson, Leif C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Biological and medical sciences Chlorides - antagonists & inhibitors Depression, Chemical Enzyme Induction - drug effects Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Inositol - pharmacology Lithium - antagonists & inhibitors Lithium Chloride Lymphocyte Activation - drug effects Organs and cells involved in the immune response Ornithine Decarboxylase - biosynthesis Phosphatidylinositols - metabolism T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - metabolism
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