The prognostic significance of age and pattern of metastases in stage IV‐S neuroblastoma
Stage IV‐S neuroblastoma is a unique disseminated neoplasia characterized by remote disease to the liver, skin, or bone marrow. Stage IV‐S patients have frequent spontaneous remissions and a 60% to 90% survival rate. Many investigators have recommended minimal or no therapeutic intervention; however...
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| Veröffentlicht in: | Cancer 1986-07, Vol.58 (2), p.372-375 |
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| container_title | Cancer |
| container_volume | 58 |
| creator | Stephenson, Stephen R. Cook, Bruce A. Mease, A. D. Ruymann, F. B. |
| description | Stage IV‐S neuroblastoma is a unique disseminated neoplasia characterized by remote disease to the liver, skin, or bone marrow. Stage IV‐S patients have frequent spontaneous remissions and a 60% to 90% survival rate. Many investigators have recommended minimal or no therapeutic intervention; however, some patients do experience progressive disease and ultimately die of neuroblastoma. Many authors have commented on single prognostic factors such as age and site of metastatic involvement. Five newborns were recently seen at Walter Reed Army Medical Center with Stage IV‐S neuroblastoma. Four of these children died of mechanical complications associated with massive hepatomegaly, prompting this review of Stage IV‐S neuroblastoma to determine prognostic factors. Cancer 58:372–375, 1986. |
| doi_str_mv | 10.1002/1097-0142(19860715)58:2<372::AID-CNCR2820580229>3.0.CO;2-2 |
| format | Article |
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Cancer 58:372–375, 1986.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19860715)58:2<372::AID-CNCR2820580229>3.0.CO;2-2</identifier><identifier>PMID: 3719530</identifier><identifier>CODEN: CANCAR</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Age Factors ; Biological and medical sciences ; Bone Marrow ; Female ; Humans ; Infant ; Liver Neoplasms - secondary ; Male ; Medical sciences ; Neoplasm Metastasis ; Neuroblastoma - mortality ; Neuroblastoma - pathology ; Neurology ; Prognosis ; Retrospective Studies ; Skin Neoplasms - secondary ; Tumors of the nervous system. 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Cancer 58:372–375, 1986.</description><subject>Age Factors</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Liver Neoplasms - secondary</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neoplasm Metastasis</subject><subject>Neuroblastoma - mortality</subject><subject>Neuroblastoma - pathology</subject><subject>Neurology</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Skin Neoplasms - secondary</subject><subject>Tumors of the nervous system. 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Phacomatoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stephenson, Stephen R.</creatorcontrib><creatorcontrib>Cook, Bruce A.</creatorcontrib><creatorcontrib>Mease, A. D.</creatorcontrib><creatorcontrib>Ruymann, F. B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stephenson, Stephen R.</au><au>Cook, Bruce A.</au><au>Mease, A. D.</au><au>Ruymann, F. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prognostic significance of age and pattern of metastases in stage IV‐S neuroblastoma</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1986-07-15</date><risdate>1986</risdate><volume>58</volume><issue>2</issue><spage>372</spage><epage>375</epage><pages>372-375</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>Stage IV‐S neuroblastoma is a unique disseminated neoplasia characterized by remote disease to the liver, skin, or bone marrow. Stage IV‐S patients have frequent spontaneous remissions and a 60% to 90% survival rate. Many investigators have recommended minimal or no therapeutic intervention; however, some patients do experience progressive disease and ultimately die of neuroblastoma. Many authors have commented on single prognostic factors such as age and site of metastatic involvement. 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| ispartof | Cancer, 1986-07, Vol.58 (2), p.372-375 |
| issn | 0008-543X 1097-0142 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Age Factors Biological and medical sciences Bone Marrow Female Humans Infant Liver Neoplasms - secondary Male Medical sciences Neoplasm Metastasis Neuroblastoma - mortality Neuroblastoma - pathology Neurology Prognosis Retrospective Studies Skin Neoplasms - secondary Tumors of the nervous system. Phacomatoses |
| title | The prognostic significance of age and pattern of metastases in stage IV‐S neuroblastoma |
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