Characterization of the Human Lymphocyte β-Adrenergic Receptor by Photoaffinity Labeling: Alterations with Desensitization

Desensitization of the leukocyte β-receptor system has been associated with a functional uncoupling of the components of the β-receptor complex. In order to determine whether desensitization and uncoupling of the leukocyte β-receptor is associated with any structural alterations in the β-receptor, w...

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Veröffentlicht in:	Circulation research 1986-03, Vol.58 (3), p.384-388
Hauptverfasser:	Feldman, Ross D, Lai, Chein-Yu Cynthia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Affinity Labels Azides beta -adrenergic Biological and medical sciences Cell Membrane - metabolism Cell receptors Cell structures and functions Fundamental and applied biological sciences. Psychology Humans Isoproterenol - pharmacology lymphocytes Lymphocytes - drug effects Lymphocytes - metabolism man Molecular and cellular biology photoaffinity labelling Photochemistry Propanolamines Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - metabolism
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