Contrast echocardiography
Myocardial contrast echocardiography (MCE) is an ultrasound imaging technique which promises to provide a safe, noninvasive means of assessing myocardial perfusion. A contrast agent, consisting of a suspension of air-filled microspheres, serves as an ultrasound tracer. When these microspheres are in...
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| Veröffentlicht in: | Ultrasound in Medicine & Biology 1994, Vol.20 (6), p.507-515 |
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| container_title | Ultrasound in Medicine & Biology |
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| creator | Winkelmann, J.W. Kenner, M.D. Dave, R. Chandwaney, R.H. Feinstein, S.B. |
| description | Myocardial contrast echocardiography (MCE) is an ultrasound imaging technique which promises to provide a safe, noninvasive means of assessing myocardial perfusion. A contrast agent, consisting of a suspension of air-filled microspheres, serves as an ultrasound tracer. When these microspheres are injected intravascularly, the acoustic interface created between the blood and the microspheres enhances the reflected ultrasound signals. Thus, the flow pattern of the microspheres represent the actual blood flow patterns. This paper will review the field of contrast echocardiography, its background and history, the development of ultrasound contrast agents, and a variety of experimental as well as clinical uses. Contrast echocardiography has been utilized in the cardiac catheterization laboratory for the assessment of “risk area”, assessment of collateral blood flow and assessment of coronary blood reserve. In the operating room, contrast echo is utilized for the determination of cardioplegic perfusion, assessment of graft patency and evaluation of valvular regurgitation. In the future, with the technical advancement in ultrasound imaging and the active interest and growth in the field of myocardial perfusion imaging using contrast echocardiography, the ability to provide routine real-time perfusion imaging may become a reality. |
| doi_str_mv | 10.1016/0301-5629(94)90086-8 |
| format | Article |
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A contrast agent, consisting of a suspension of air-filled microspheres, serves as an ultrasound tracer. When these microspheres are injected intravascularly, the acoustic interface created between the blood and the microspheres enhances the reflected ultrasound signals. Thus, the flow pattern of the microspheres represent the actual blood flow patterns. This paper will review the field of contrast echocardiography, its background and history, the development of ultrasound contrast agents, and a variety of experimental as well as clinical uses. Contrast echocardiography has been utilized in the cardiac catheterization laboratory for the assessment of “risk area”, assessment of collateral blood flow and assessment of coronary blood reserve. In the operating room, contrast echo is utilized for the determination of cardioplegic perfusion, assessment of graft patency and evaluation of valvular regurgitation. 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A contrast agent, consisting of a suspension of air-filled microspheres, serves as an ultrasound tracer. When these microspheres are injected intravascularly, the acoustic interface created between the blood and the microspheres enhances the reflected ultrasound signals. Thus, the flow pattern of the microspheres represent the actual blood flow patterns. This paper will review the field of contrast echocardiography, its background and history, the development of ultrasound contrast agents, and a variety of experimental as well as clinical uses. Contrast echocardiography has been utilized in the cardiac catheterization laboratory for the assessment of “risk area”, assessment of collateral blood flow and assessment of coronary blood reserve. In the operating room, contrast echo is utilized for the determination of cardioplegic perfusion, assessment of graft patency and evaluation of valvular regurgitation. In the future, with the technical advancement in ultrasound imaging and the active interest and growth in the field of myocardial perfusion imaging using contrast echocardiography, the ability to provide routine real-time perfusion imaging may become a reality.</description><subject>Albumins</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>Contrast agents</subject><subject>Contrast Media</subject><subject>Coronary Circulation</subject><subject>Echocardiography - history</subject><subject>History of medicine</subject><subject>History, 20th Century</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Microspheres</subject><subject>Myocardial perfusion</subject><subject>Quantitation of blood flow</subject><subject>Sonication techniques</subject><subject>Ultrasonic investigative techniques</subject><subject>Ultrasound imaging</subject><issn>0301-5629</issn><issn>1879-291X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotVZ_gKDgQUQPq8lumslcBCl-QcGLgreQTbI2st2tyVbovze1S496Gph53pfhIeSE0WtGmbihBWXZWOR4ifwKKZUikztkyCRgliN73yXDLbJPDmL8pJSCKGBABoAoC2BDcjxpmy7o2J05M2uNDta3H0EvZqtDslfpOrqjfo7I28P96-Qpm748Pk_uppnhDLqMp3ZacS7Z2GFpKeYSjUkbCVyWFqwRRQk052mnndUyhxK0xZSrQJasGJGLTe8itF9LFzs199G4utaNa5dRgZASeUH_BZmQCIlNIN-AJrQxBlepRfBzHVaKUbVWp9Ze1NqLQq5-1SmZYqd9_7KcO7sN9a7S_by_62h0XQXdGB-3GM8FIEDCbjeYS9K-vQsqGu8a46wPznTKtv7vP34AJ-2IJA</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>Winkelmann, J.W.</creator><creator>Kenner, M.D.</creator><creator>Dave, R.</creator><creator>Chandwaney, R.H.</creator><creator>Feinstein, S.B.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>Contrast echocardiography</title><author>Winkelmann, J.W. ; Kenner, M.D. ; Dave, R. ; Chandwaney, R.H. ; Feinstein, S.B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-46290f44815e9bd09289cc0f48748bd7dc63b7024c0faeda827b7ad9462f78b13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Albumins</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular system</topic><topic>Contrast agents</topic><topic>Contrast Media</topic><topic>Coronary Circulation</topic><topic>Echocardiography - history</topic><topic>History of medicine</topic><topic>History, 20th Century</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Microspheres</topic><topic>Myocardial perfusion</topic><topic>Quantitation of blood flow</topic><topic>Sonication techniques</topic><topic>Ultrasonic investigative techniques</topic><topic>Ultrasound imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Winkelmann, J.W.</creatorcontrib><creatorcontrib>Kenner, M.D.</creatorcontrib><creatorcontrib>Dave, R.</creatorcontrib><creatorcontrib>Chandwaney, R.H.</creatorcontrib><creatorcontrib>Feinstein, S.B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Ultrasound in Medicine & Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Winkelmann, J.W.</au><au>Kenner, M.D.</au><au>Dave, R.</au><au>Chandwaney, R.H.</au><au>Feinstein, S.B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contrast echocardiography</atitle><jtitle>Ultrasound in Medicine & Biology</jtitle><addtitle>Ultrasound Med Biol</addtitle><date>1994</date><risdate>1994</risdate><volume>20</volume><issue>6</issue><spage>507</spage><epage>515</epage><pages>507-515</pages><issn>0301-5629</issn><eissn>1879-291X</eissn><coden>USMBA3</coden><abstract>Myocardial contrast echocardiography (MCE) is an ultrasound imaging technique which promises to provide a safe, noninvasive means of assessing myocardial perfusion. 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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Albumins Biological and medical sciences Cardiovascular system Contrast agents Contrast Media Coronary Circulation Echocardiography - history History of medicine History, 20th Century Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Microspheres Myocardial perfusion Quantitation of blood flow Sonication techniques Ultrasonic investigative techniques Ultrasound imaging |
| title | Contrast echocardiography |
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