Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P
The present study first shows that calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) nerve fibers in the cerebral arteries contained substance P (SP) and originated from small- to medium-sized CGRPI cells exhibiting SP immunoreactivity (SPI) in the trigeminal ganglion. The iris cont...
Gespeichert in:
| Veröffentlicht in: | Brain research 1986-05, Vol.373 (1), p.205-212 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 212 |
|---|---|
| container_issue | 1 |
| container_start_page | 205 |
| container_title | Brain research |
| container_volume | 373 |
| creator | Matsuyama, Tomohiro Wanaka, Akio Yoneda, Shotaro Kimura, Kazufumi Kamada, Takenobu Girgis, Samia Macintyre, Iain Emson, Piers C. Tohyama, Masaya |
| description | The present study first shows that calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) nerve fibers in the cerebral arteries contained substance P (SP) and originated from small- to medium-sized CGRPI cells exhibiting SP immunoreactivity (SPI) in the trigeminal ganglion. The iris contained CGRPI/SPI-costorage nerve fibers and many CGRPI fibers lacking SPI. These fibers originated from large CGRPI cells lacking SPI in the trigeminal ganglion. The heterogenous subpopulations of CGRPI fibers in the iris suggest that CGRP is involved in a variety of functions in this structure. |
| doi_str_mv | 10.1016/0006-8993(86)90332-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76888153</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>000689938690332X</els_id><sourcerecordid>76888153</sourcerecordid><originalsourceid>FETCH-LOGICAL-c303t-527ee0db6726a2cf93197c6322f3433c17f0b70581cc7fefa631b8c2cd56891f3</originalsourceid><addsrcrecordid>eNqFUctu1DAUjRCoDIU_AMkrBIuAHxPHYVEJladUCRZF6s5ynJvORRkntW9mNH_IZ-F0Rl3Cyrr3PK58TlG8FPyd4EK_55zr0jSNemP024YrJcubR8VKmFqWWq7542L1QHlaPEvpdx6VavhZcSbXcl1VYlX8ud6PrMNEGDwx7waPNAYM7BYClBEGR9CxCSbCDko_BnKY4du8ijhtILqBBYi7cU4sHRLBNn1gn7JfxHYmHANzoWN3swuE5Ah3kK_1PUQIHhJrgfYAgdEGGEZM92yf0XYxdpEgHtgeacPSBB7zLsJJzGhkaW4TuWX4-bx40rshwYvTe178-vL5-vJbefXj6_fLj1elV1xRWckagHetrqV20veNEk3ttZKyV2ulvKh73ta8MsL7uofeaSVa46XvKm0a0avz4vXRd4rj3QyJ7BaTh2FwAXIIttbGGFGp_xJFLsBIzTNxfST6OKaU_2eniFsXD1ZwuzRtlxrtUqM12t43bW-y7NXJf2630D2ITtVm_OKIQ05jhxBt8rgE12EET7Yb8d8H_gKy475D</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14558260</pqid></control><display><type>article</type><title>Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Collection</source><creator>Matsuyama, Tomohiro ; Wanaka, Akio ; Yoneda, Shotaro ; Kimura, Kazufumi ; Kamada, Takenobu ; Girgis, Samia ; Macintyre, Iain ; Emson, Piers C. ; Tohyama, Masaya</creator><creatorcontrib>Matsuyama, Tomohiro ; Wanaka, Akio ; Yoneda, Shotaro ; Kimura, Kazufumi ; Kamada, Takenobu ; Girgis, Samia ; Macintyre, Iain ; Emson, Piers C. ; Tohyama, Masaya</creatorcontrib><description>The present study first shows that calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) nerve fibers in the cerebral arteries contained substance P (SP) and originated from small- to medium-sized CGRPI cells exhibiting SP immunoreactivity (SPI) in the trigeminal ganglion. The iris contained CGRPI/SPI-costorage nerve fibers and many CGRPI fibers lacking SPI. These fibers originated from large CGRPI cells lacking SPI in the trigeminal ganglion. The heterogenous subpopulations of CGRPI fibers in the iris suggest that CGRP is involved in a variety of functions in this structure.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(86)90332-X</identifier><identifier>PMID: 2424551</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Animals, Newborn ; Calcitonin Gene-Related Peptide ; capsaicin ; Capsaicin - pharmacology ; Cerebral Arteries - innervation ; cerebral artery ; Fluorescent Antibody Technique ; immunohistochemistry ; iris ; Iris - innervation ; neonatal rat ; Nerve Fibers - metabolism ; Nerve Tissue Proteins - metabolism ; Rats ; substance P ; Substance P - metabolism ; Trigeminal Ganglion - metabolism ; Trigeminal Nerve - metabolism ; Trigeminal Nucleus, Spinal - metabolism</subject><ispartof>Brain research, 1986-05, Vol.373 (1), p.205-212</ispartof><rights>1986 Elsevier Science Publishers B.V. (Biomedical Division)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c303t-527ee0db6726a2cf93197c6322f3433c17f0b70581cc7fefa631b8c2cd56891f3</citedby><cites>FETCH-LOGICAL-c303t-527ee0db6726a2cf93197c6322f3433c17f0b70581cc7fefa631b8c2cd56891f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/000689938690332X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2424551$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Matsuyama, Tomohiro</creatorcontrib><creatorcontrib>Wanaka, Akio</creatorcontrib><creatorcontrib>Yoneda, Shotaro</creatorcontrib><creatorcontrib>Kimura, Kazufumi</creatorcontrib><creatorcontrib>Kamada, Takenobu</creatorcontrib><creatorcontrib>Girgis, Samia</creatorcontrib><creatorcontrib>Macintyre, Iain</creatorcontrib><creatorcontrib>Emson, Piers C.</creatorcontrib><creatorcontrib>Tohyama, Masaya</creatorcontrib><title>Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>The present study first shows that calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) nerve fibers in the cerebral arteries contained substance P (SP) and originated from small- to medium-sized CGRPI cells exhibiting SP immunoreactivity (SPI) in the trigeminal ganglion. The iris contained CGRPI/SPI-costorage nerve fibers and many CGRPI fibers lacking SPI. These fibers originated from large CGRPI cells lacking SPI in the trigeminal ganglion. The heterogenous subpopulations of CGRPI fibers in the iris suggest that CGRP is involved in a variety of functions in this structure.</description><subject>Animals</subject><subject>Animals, Newborn</subject><subject>Calcitonin Gene-Related Peptide</subject><subject>capsaicin</subject><subject>Capsaicin - pharmacology</subject><subject>Cerebral Arteries - innervation</subject><subject>cerebral artery</subject><subject>Fluorescent Antibody Technique</subject><subject>immunohistochemistry</subject><subject>iris</subject><subject>Iris - innervation</subject><subject>neonatal rat</subject><subject>Nerve Fibers - metabolism</subject><subject>Nerve Tissue Proteins - metabolism</subject><subject>Rats</subject><subject>substance P</subject><subject>Substance P - metabolism</subject><subject>Trigeminal Ganglion - metabolism</subject><subject>Trigeminal Nerve - metabolism</subject><subject>Trigeminal Nucleus, Spinal - metabolism</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUctu1DAUjRCoDIU_AMkrBIuAHxPHYVEJladUCRZF6s5ynJvORRkntW9mNH_IZ-F0Rl3Cyrr3PK58TlG8FPyd4EK_55zr0jSNemP024YrJcubR8VKmFqWWq7542L1QHlaPEvpdx6VavhZcSbXcl1VYlX8ud6PrMNEGDwx7waPNAYM7BYClBEGR9CxCSbCDko_BnKY4du8ijhtILqBBYi7cU4sHRLBNn1gn7JfxHYmHANzoWN3swuE5Ah3kK_1PUQIHhJrgfYAgdEGGEZM92yf0XYxdpEgHtgeacPSBB7zLsJJzGhkaW4TuWX4-bx40rshwYvTe178-vL5-vJbefXj6_fLj1elV1xRWckagHetrqV20veNEk3ttZKyV2ulvKh73ta8MsL7uofeaSVa46XvKm0a0avz4vXRd4rj3QyJ7BaTh2FwAXIIttbGGFGp_xJFLsBIzTNxfST6OKaU_2eniFsXD1ZwuzRtlxrtUqM12t43bW-y7NXJf2630D2ITtVm_OKIQ05jhxBt8rgE12EET7Yb8d8H_gKy475D</recordid><startdate>19860514</startdate><enddate>19860514</enddate><creator>Matsuyama, Tomohiro</creator><creator>Wanaka, Akio</creator><creator>Yoneda, Shotaro</creator><creator>Kimura, Kazufumi</creator><creator>Kamada, Takenobu</creator><creator>Girgis, Samia</creator><creator>Macintyre, Iain</creator><creator>Emson, Piers C.</creator><creator>Tohyama, Masaya</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19860514</creationdate><title>Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P</title><author>Matsuyama, Tomohiro ; Wanaka, Akio ; Yoneda, Shotaro ; Kimura, Kazufumi ; Kamada, Takenobu ; Girgis, Samia ; Macintyre, Iain ; Emson, Piers C. ; Tohyama, Masaya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c303t-527ee0db6726a2cf93197c6322f3433c17f0b70581cc7fefa631b8c2cd56891f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Animals, Newborn</topic><topic>Calcitonin Gene-Related Peptide</topic><topic>capsaicin</topic><topic>Capsaicin - pharmacology</topic><topic>Cerebral Arteries - innervation</topic><topic>cerebral artery</topic><topic>Fluorescent Antibody Technique</topic><topic>immunohistochemistry</topic><topic>iris</topic><topic>Iris - innervation</topic><topic>neonatal rat</topic><topic>Nerve Fibers - metabolism</topic><topic>Nerve Tissue Proteins - metabolism</topic><topic>Rats</topic><topic>substance P</topic><topic>Substance P - metabolism</topic><topic>Trigeminal Ganglion - metabolism</topic><topic>Trigeminal Nerve - metabolism</topic><topic>Trigeminal Nucleus, Spinal - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Matsuyama, Tomohiro</creatorcontrib><creatorcontrib>Wanaka, Akio</creatorcontrib><creatorcontrib>Yoneda, Shotaro</creatorcontrib><creatorcontrib>Kimura, Kazufumi</creatorcontrib><creatorcontrib>Kamada, Takenobu</creatorcontrib><creatorcontrib>Girgis, Samia</creatorcontrib><creatorcontrib>Macintyre, Iain</creatorcontrib><creatorcontrib>Emson, Piers C.</creatorcontrib><creatorcontrib>Tohyama, Masaya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matsuyama, Tomohiro</au><au>Wanaka, Akio</au><au>Yoneda, Shotaro</au><au>Kimura, Kazufumi</au><au>Kamada, Takenobu</au><au>Girgis, Samia</au><au>Macintyre, Iain</au><au>Emson, Piers C.</au><au>Tohyama, Masaya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1986-05-14</date><risdate>1986</risdate><volume>373</volume><issue>1</issue><spage>205</spage><epage>212</epage><pages>205-212</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><abstract>The present study first shows that calcitonin gene-related peptide (CGRP)-like immunoreactive (CGRPI) nerve fibers in the cerebral arteries contained substance P (SP) and originated from small- to medium-sized CGRPI cells exhibiting SP immunoreactivity (SPI) in the trigeminal ganglion. The iris contained CGRPI/SPI-costorage nerve fibers and many CGRPI fibers lacking SPI. These fibers originated from large CGRPI cells lacking SPI in the trigeminal ganglion. The heterogenous subpopulations of CGRPI fibers in the iris suggest that CGRP is involved in a variety of functions in this structure.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>2424551</pmid><doi>10.1016/0006-8993(86)90332-X</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 1986-05, Vol.373 (1), p.205-212 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76888153 |
| source | MEDLINE; Elsevier ScienceDirect Journals Collection |
| subjects | Animals Animals, Newborn Calcitonin Gene-Related Peptide capsaicin Capsaicin - pharmacology Cerebral Arteries - innervation cerebral artery Fluorescent Antibody Technique immunohistochemistry iris Iris - innervation neonatal rat Nerve Fibers - metabolism Nerve Tissue Proteins - metabolism Rats substance P Substance P - metabolism Trigeminal Ganglion - metabolism Trigeminal Nerve - metabolism Trigeminal Nucleus, Spinal - metabolism |
| title | Two distinct calcitonin gene-related peptide-containing peripheral nervous systems: Distribution and quantitative differences between the iris and cerebral artery with special reference to substance P |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T15%3A09%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Two%20distinct%20calcitonin%20gene-related%20peptide-containing%20peripheral%20nervous%20systems:%20Distribution%20and%20quantitative%20differences%20between%20the%20iris%20and%20cerebral%20artery%20with%20special%20reference%20to%20substance%20P&rft.jtitle=Brain%20research&rft.au=Matsuyama,%20Tomohiro&rft.date=1986-05-14&rft.volume=373&rft.issue=1&rft.spage=205&rft.epage=212&rft.pages=205-212&rft.issn=0006-8993&rft.eissn=1872-6240&rft_id=info:doi/10.1016/0006-8993(86)90332-X&rft_dat=%3Cproquest_cross%3E76888153%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14558260&rft_id=info:pmid/2424551&rft_els_id=000689938690332X&rfr_iscdi=true |