Undifferentiated Tumors: An Immunohistochemical Analysis on Biopsies
Immunohistochemical staining was performed on 145 biopsies with a diagnosis of undifferentiated or poorly differentiated tumor in order to classify them into lymphoid, epithelial, or mesenchymal in origin. It was possible to arrive at a histogenetic diagnosis on immunostaining in 85.5% of cases. Imm...
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Veröffentlicht in: | Journal of surgical oncology 1994-12, Vol.57 (4), p.273-276 |
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container_title | Journal of surgical oncology |
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creator | Vege, Durga S. Soman, Chitralekha S. Joshi, Ujjwala A. Yadav, Jyoti N. Ganesh, Balasubramaniam |
description | Immunohistochemical staining was performed on 145 biopsies with a diagnosis of undifferentiated or poorly differentiated tumor in order to classify them into lymphoid, epithelial, or mesenchymal in origin. It was possible to arrive at a histogenetic diagnosis on immunostaining in 85.5% of cases. Immunostaining confirmed the diagnosis in 32.4% and contributed to diagnosis in 53.1%. Malignant lymphoma was the most common diagnosis (35.9%), followed by carcinoma (23.4%). A panel of antibodies consisting of anti‐common leucocyte antigen (LCA), anti‐epithelial membrane antigen (EMA), anti‐cytokeratin (CK), anti‐low to intermediate molecular weight cytokeratin (CAM 5.2), anti‐S‐100 protein (S‐100), and anti‐vimentin (VM) may resolve, to a large extent, some of the common diagnostic problems. © 1994 Wiley‐Liss, Inc. |
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It was possible to arrive at a histogenetic diagnosis on immunostaining in 85.5% of cases. Immunostaining confirmed the diagnosis in 32.4% and contributed to diagnosis in 53.1%. Malignant lymphoma was the most common diagnosis (35.9%), followed by carcinoma (23.4%). A panel of antibodies consisting of anti‐common leucocyte antigen (LCA), anti‐epithelial membrane antigen (EMA), anti‐cytokeratin (CK), anti‐low to intermediate molecular weight cytokeratin (CAM 5.2), anti‐S‐100 protein (S‐100), and anti‐vimentin (VM) may resolve, to a large extent, some of the common diagnostic problems. © 1994 Wiley‐Liss, Inc.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930570414</identifier><identifier>PMID: 7990486</identifier><identifier>CODEN: JSONAU</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>anti-common leucocyte antigen ; anti-cytokeratin ; anti-epithelial membrane antigen ; anti-S-100 protein ; anti-vimentin ; Antibodies, Neoplasm - analysis ; Biological and medical sciences ; Biopsy ; Carcinoma - diagnosis ; Carcinoma - immunology ; Diagnosis, Differential ; Host-tumor relations. Immunology. Biological markers ; Humans ; Immunohistochemistry ; Lymphoma - diagnosis ; Lymphoma - immunology ; Medical sciences ; Tumors</subject><ispartof>Journal of surgical oncology, 1994-12, Vol.57 (4), p.273-276</ispartof><rights>Copyright © 1994 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4074-449fdbd47cc8119f573395983a4ba832424700dd9feb7f77d331b24bfaa411853</citedby><cites>FETCH-LOGICAL-c4074-449fdbd47cc8119f573395983a4ba832424700dd9feb7f77d331b24bfaa411853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930570414$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930570414$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3384443$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7990486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vege, Durga S.</creatorcontrib><creatorcontrib>Soman, Chitralekha S.</creatorcontrib><creatorcontrib>Joshi, Ujjwala A.</creatorcontrib><creatorcontrib>Yadav, Jyoti N.</creatorcontrib><creatorcontrib>Ganesh, Balasubramaniam</creatorcontrib><title>Undifferentiated Tumors: An Immunohistochemical Analysis on Biopsies</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>Immunohistochemical staining was performed on 145 biopsies with a diagnosis of undifferentiated or poorly differentiated tumor in order to classify them into lymphoid, epithelial, or mesenchymal in origin. It was possible to arrive at a histogenetic diagnosis on immunostaining in 85.5% of cases. Immunostaining confirmed the diagnosis in 32.4% and contributed to diagnosis in 53.1%. Malignant lymphoma was the most common diagnosis (35.9%), followed by carcinoma (23.4%). A panel of antibodies consisting of anti‐common leucocyte antigen (LCA), anti‐epithelial membrane antigen (EMA), anti‐cytokeratin (CK), anti‐low to intermediate molecular weight cytokeratin (CAM 5.2), anti‐S‐100 protein (S‐100), and anti‐vimentin (VM) may resolve, to a large extent, some of the common diagnostic problems. © 1994 Wiley‐Liss, Inc.</description><subject>anti-common leucocyte antigen</subject><subject>anti-cytokeratin</subject><subject>anti-epithelial membrane antigen</subject><subject>anti-S-100 protein</subject><subject>anti-vimentin</subject><subject>Antibodies, Neoplasm - analysis</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Carcinoma - diagnosis</subject><subject>Carcinoma - immunology</subject><subject>Diagnosis, Differential</subject><subject>Host-tumor relations. Immunology. Biological markers</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Lymphoma - diagnosis</subject><subject>Lymphoma - immunology</subject><subject>Medical sciences</subject><subject>Tumors</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1v2zAQhomiheOkXbsF0FB0k0OKJ5HMlrhpkiIfg220G0FJJExXEh2ehcT_vgpsuMiU6YC75707PIR8ZXTCKM3OVhgmmeI0FxQYfCBjRlWRKqrkRzIegCwFoegROUZcUUqVKmBERkIpCrIYkx-LrvbO2Wi7jTcbWyfzvg0Rz5OLLrlt274LS4-bUC1t6yvTDG3TbNFjErrk0oc1eoufySdnGrRf9vWELH5ezac36d3j9e304i6tgApIAZSryxpEVUnGlMsF5ypXkhsojeQZZCAorWvlbCmcEDXnrMygdMYAYzLnJ-T7bu86hqfe4ka3HivbNKazoUctCilkpl7ByQ6sYkCM1ul19K2JW82oftWmB236v7YhcLrf3JetrQ_43tMw_7afGxwsuGi6yuMB41wCAB8wtcOefWO37xzVv2aPb15Id9lBt305ZE38qwvBRa5_P1xrfv9nfn85m-oZ_wdKd5TX</recordid><startdate>199412</startdate><enddate>199412</enddate><creator>Vege, Durga S.</creator><creator>Soman, Chitralekha S.</creator><creator>Joshi, Ujjwala A.</creator><creator>Yadav, Jyoti N.</creator><creator>Ganesh, Balasubramaniam</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199412</creationdate><title>Undifferentiated Tumors: An Immunohistochemical Analysis on Biopsies</title><author>Vege, Durga S. ; Soman, Chitralekha S. ; Joshi, Ujjwala A. ; Yadav, Jyoti N. ; Ganesh, Balasubramaniam</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4074-449fdbd47cc8119f573395983a4ba832424700dd9feb7f77d331b24bfaa411853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>anti-common leucocyte antigen</topic><topic>anti-cytokeratin</topic><topic>anti-epithelial membrane antigen</topic><topic>anti-S-100 protein</topic><topic>anti-vimentin</topic><topic>Antibodies, Neoplasm - analysis</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Carcinoma - diagnosis</topic><topic>Carcinoma - immunology</topic><topic>Diagnosis, Differential</topic><topic>Host-tumor relations. Immunology. Biological markers</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Lymphoma - diagnosis</topic><topic>Lymphoma - immunology</topic><topic>Medical sciences</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vege, Durga S.</creatorcontrib><creatorcontrib>Soman, Chitralekha S.</creatorcontrib><creatorcontrib>Joshi, Ujjwala A.</creatorcontrib><creatorcontrib>Yadav, Jyoti N.</creatorcontrib><creatorcontrib>Ganesh, Balasubramaniam</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vege, Durga S.</au><au>Soman, Chitralekha S.</au><au>Joshi, Ujjwala A.</au><au>Yadav, Jyoti N.</au><au>Ganesh, Balasubramaniam</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Undifferentiated Tumors: An Immunohistochemical Analysis on Biopsies</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1994-12</date><risdate>1994</risdate><volume>57</volume><issue>4</issue><spage>273</spage><epage>276</epage><pages>273-276</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><coden>JSONAU</coden><abstract>Immunohistochemical staining was performed on 145 biopsies with a diagnosis of undifferentiated or poorly differentiated tumor in order to classify them into lymphoid, epithelial, or mesenchymal in origin. It was possible to arrive at a histogenetic diagnosis on immunostaining in 85.5% of cases. Immunostaining confirmed the diagnosis in 32.4% and contributed to diagnosis in 53.1%. Malignant lymphoma was the most common diagnosis (35.9%), followed by carcinoma (23.4%). A panel of antibodies consisting of anti‐common leucocyte antigen (LCA), anti‐epithelial membrane antigen (EMA), anti‐cytokeratin (CK), anti‐low to intermediate molecular weight cytokeratin (CAM 5.2), anti‐S‐100 protein (S‐100), and anti‐vimentin (VM) may resolve, to a large extent, some of the common diagnostic problems. © 1994 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>7990486</pmid><doi>10.1002/jso.2930570414</doi><tpages>4</tpages></addata></record> |
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subjects | anti-common leucocyte antigen anti-cytokeratin anti-epithelial membrane antigen anti-S-100 protein anti-vimentin Antibodies, Neoplasm - analysis Biological and medical sciences Biopsy Carcinoma - diagnosis Carcinoma - immunology Diagnosis, Differential Host-tumor relations. Immunology. Biological markers Humans Immunohistochemistry Lymphoma - diagnosis Lymphoma - immunology Medical sciences Tumors |
title | Undifferentiated Tumors: An Immunohistochemical Analysis on Biopsies |
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