Diagnosis of germinal neoplasm in the thalamus and basal ganglia
Germinal neoplasms originating in the thalamus and basal ganglia were histologically verified by stereotactic biopsies in five cases and by other methods in three cases. Immunoperoxidase staining was performed on the tumors using antibodies against human chorionic gonadotropin and placental alkaline...
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Veröffentlicht in: | Surgical neurology 1986-07, Vol.26 (1), p.24-28 |
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creator | Ono, Nobuo Inoue, Hiroshi K. Naganuma, Hirofumi Kunimine, Hideo Zama, Akira Tamura, Masaru |
description | Germinal neoplasms originating in the thalamus and basal ganglia were histologically verified by stereotactic biopsies in five cases and by other methods in three cases. Immunoperoxidase staining was performed on the tumors using antibodies against human chorionic gonadotropin and placental alkaline phosphatase. The presence of human chorionic gonadotropin was demonstrated in one germinoma and two mixed tumors, but not in three germinomas. Placental alkaline phosphatase was demonstrated to be present in four germinomas and one mixed tumor. Stereotactic biopsy specimens can be studied immunohistochemically, and the placental isoenzyme of alkaline phosphatase appears to be a new tumor marker for germinoma. |
doi_str_mv | 10.1016/0090-3019(86)90059-5 |
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Immunoperoxidase staining was performed on the tumors using antibodies against human chorionic gonadotropin and placental alkaline phosphatase. The presence of human chorionic gonadotropin was demonstrated in one germinoma and two mixed tumors, but not in three germinomas. Placental alkaline phosphatase was demonstrated to be present in four germinomas and one mixed tumor. Stereotactic biopsy specimens can be studied immunohistochemically, and the placental isoenzyme of alkaline phosphatase appears to be a new tumor marker for germinoma.</description><identifier>ISSN: 0090-3019</identifier><identifier>EISSN: 1879-3339</identifier><identifier>DOI: 10.1016/0090-3019(86)90059-5</identifier><identifier>PMID: 3715696</identifier><identifier>CODEN: SGNRAI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Basal ganglia ; Basal Ganglia Diseases - diagnostic imaging ; Basal Ganglia Diseases - pathology ; Biological and medical sciences ; Brain Neoplasms - analysis ; Brain Neoplasms - diagnostic imaging ; Brain Neoplasms - pathology ; Child ; Dysgerminoma - analysis ; Dysgerminoma - diagnostic imaging ; Dysgerminoma - pathology ; Female ; Germinoma ; Humans ; Immunochemistry ; Immunohistochemistry ; Male ; Medical sciences ; Neurology ; Placental alkaline phosphatase ; Radiography ; Stereotactic biopsy ; Thalamic Diseases - diagnostic imaging ; Thalamic Diseases - pathology ; Thalamus ; Tumors of the nervous system. Phacomatoses</subject><ispartof>Surgical neurology, 1986-07, Vol.26 (1), p.24-28</ispartof><rights>1986</rights><rights>1986 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-ac75cd03e80a0f91060d400869a0422f38a9955b783b78906969a2450734bbdb3</citedby><cites>FETCH-LOGICAL-c415t-ac75cd03e80a0f91060d400869a0422f38a9955b783b78906969a2450734bbdb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8812615$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3715696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ono, Nobuo</creatorcontrib><creatorcontrib>Inoue, Hiroshi K.</creatorcontrib><creatorcontrib>Naganuma, Hirofumi</creatorcontrib><creatorcontrib>Kunimine, Hideo</creatorcontrib><creatorcontrib>Zama, Akira</creatorcontrib><creatorcontrib>Tamura, Masaru</creatorcontrib><title>Diagnosis of germinal neoplasm in the thalamus and basal ganglia</title><title>Surgical neurology</title><addtitle>Surg Neurol</addtitle><description>Germinal neoplasms originating in the thalamus and basal ganglia were histologically verified by stereotactic biopsies in five cases and by other methods in three cases. Immunoperoxidase staining was performed on the tumors using antibodies against human chorionic gonadotropin and placental alkaline phosphatase. The presence of human chorionic gonadotropin was demonstrated in one germinoma and two mixed tumors, but not in three germinomas. Placental alkaline phosphatase was demonstrated to be present in four germinomas and one mixed tumor. Stereotactic biopsy specimens can be studied immunohistochemically, and the placental isoenzyme of alkaline phosphatase appears to be a new tumor marker for germinoma.</description><subject>Adolescent</subject><subject>Basal ganglia</subject><subject>Basal Ganglia Diseases - diagnostic imaging</subject><subject>Basal Ganglia Diseases - pathology</subject><subject>Biological and medical sciences</subject><subject>Brain Neoplasms - analysis</subject><subject>Brain Neoplasms - diagnostic imaging</subject><subject>Brain Neoplasms - pathology</subject><subject>Child</subject><subject>Dysgerminoma - analysis</subject><subject>Dysgerminoma - diagnostic imaging</subject><subject>Dysgerminoma - pathology</subject><subject>Female</subject><subject>Germinoma</subject><subject>Humans</subject><subject>Immunochemistry</subject><subject>Immunohistochemistry</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neurology</subject><subject>Placental alkaline phosphatase</subject><subject>Radiography</subject><subject>Stereotactic biopsy</subject><subject>Thalamic Diseases - diagnostic imaging</subject><subject>Thalamic Diseases - pathology</subject><subject>Thalamus</subject><subject>Tumors of the nervous system. Phacomatoses</subject><issn>0090-3019</issn><issn>1879-3339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMo6_rxDxR6ENFDddI0aXIRZf2EBS96DtM0XSP9WJNW8N_bumWPHoY5zDMvLw8hJxSuKFBxDaAgZkDVhRSXCoCrmO-QOZWZihljapfMt8g-OQjhEwCY4mpGZiyjXCgxJ7f3DldNG1yI2jJaWV-7Bquose26wlBHrom6DzsMVlj3IcKmiHIMA7LCZlU5PCJ7JVbBHk_7kLw_PrwtnuPl69PL4m4Zm5TyLkaTcVMAsxIQSkVBQJECSKEQ0iQpmUSlOM8zyYZRMJRTmKQcMpbmeZGzQ3K-yV379qu3odO1C8ZWFQ5d-6AzITPKGB_AdAMa34bgbanX3tXofzQFPYrToxU9WtFS6D9xenw7nfL7vLbF9mkyNdzPpjsGg1XpsTEubDEpaSLoGHOzwezg4ttZr4NxtjG2cN6aThet-7_HLziBh0Q</recordid><startdate>19860701</startdate><enddate>19860701</enddate><creator>Ono, Nobuo</creator><creator>Inoue, Hiroshi K.</creator><creator>Naganuma, Hirofumi</creator><creator>Kunimine, Hideo</creator><creator>Zama, Akira</creator><creator>Tamura, Masaru</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860701</creationdate><title>Diagnosis of germinal neoplasm in the thalamus and basal ganglia</title><author>Ono, Nobuo ; Inoue, Hiroshi K. ; Naganuma, Hirofumi ; Kunimine, Hideo ; Zama, Akira ; Tamura, Masaru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-ac75cd03e80a0f91060d400869a0422f38a9955b783b78906969a2450734bbdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adolescent</topic><topic>Basal ganglia</topic><topic>Basal Ganglia Diseases - diagnostic imaging</topic><topic>Basal Ganglia Diseases - pathology</topic><topic>Biological and medical sciences</topic><topic>Brain Neoplasms - analysis</topic><topic>Brain Neoplasms - diagnostic imaging</topic><topic>Brain Neoplasms - pathology</topic><topic>Child</topic><topic>Dysgerminoma - analysis</topic><topic>Dysgerminoma - diagnostic imaging</topic><topic>Dysgerminoma - pathology</topic><topic>Female</topic><topic>Germinoma</topic><topic>Humans</topic><topic>Immunochemistry</topic><topic>Immunohistochemistry</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neurology</topic><topic>Placental alkaline phosphatase</topic><topic>Radiography</topic><topic>Stereotactic biopsy</topic><topic>Thalamic Diseases - diagnostic imaging</topic><topic>Thalamic Diseases - pathology</topic><topic>Thalamus</topic><topic>Tumors of the nervous system. Phacomatoses</topic><toplevel>online_resources</toplevel><creatorcontrib>Ono, Nobuo</creatorcontrib><creatorcontrib>Inoue, Hiroshi K.</creatorcontrib><creatorcontrib>Naganuma, Hirofumi</creatorcontrib><creatorcontrib>Kunimine, Hideo</creatorcontrib><creatorcontrib>Zama, Akira</creatorcontrib><creatorcontrib>Tamura, Masaru</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgical neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ono, Nobuo</au><au>Inoue, Hiroshi K.</au><au>Naganuma, Hirofumi</au><au>Kunimine, Hideo</au><au>Zama, Akira</au><au>Tamura, Masaru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnosis of germinal neoplasm in the thalamus and basal ganglia</atitle><jtitle>Surgical neurology</jtitle><addtitle>Surg Neurol</addtitle><date>1986-07-01</date><risdate>1986</risdate><volume>26</volume><issue>1</issue><spage>24</spage><epage>28</epage><pages>24-28</pages><issn>0090-3019</issn><eissn>1879-3339</eissn><coden>SGNRAI</coden><abstract>Germinal neoplasms originating in the thalamus and basal ganglia were histologically verified by stereotactic biopsies in five cases and by other methods in three cases. Immunoperoxidase staining was performed on the tumors using antibodies against human chorionic gonadotropin and placental alkaline phosphatase. The presence of human chorionic gonadotropin was demonstrated in one germinoma and two mixed tumors, but not in three germinomas. Placental alkaline phosphatase was demonstrated to be present in four germinomas and one mixed tumor. Stereotactic biopsy specimens can be studied immunohistochemically, and the placental isoenzyme of alkaline phosphatase appears to be a new tumor marker for germinoma.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3715696</pmid><doi>10.1016/0090-3019(86)90059-5</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Basal ganglia Basal Ganglia Diseases - diagnostic imaging Basal Ganglia Diseases - pathology Biological and medical sciences Brain Neoplasms - analysis Brain Neoplasms - diagnostic imaging Brain Neoplasms - pathology Child Dysgerminoma - analysis Dysgerminoma - diagnostic imaging Dysgerminoma - pathology Female Germinoma Humans Immunochemistry Immunohistochemistry Male Medical sciences Neurology Placental alkaline phosphatase Radiography Stereotactic biopsy Thalamic Diseases - diagnostic imaging Thalamic Diseases - pathology Thalamus Tumors of the nervous system. Phacomatoses |
title | Diagnosis of germinal neoplasm in the thalamus and basal ganglia |
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