Identification of serotonin 5-HT4 recognition sites in the porcine caudate nucleus by radioligand binding

Specific binding for the serotonin 5-HT4 receptor (5-HT4R) radioligand [3H]GR 113808 was identified in pig caudate nucleus and characterized by serotonin subtype selective drugs. Binding was inhibited by serotonin and by synthetic indoles, benzamides and benzimidazolones known to characterize the 5-...

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Veröffentlicht in:	Neuropharmacology 1994-03, Vol.33 (3-4), p.543-549
Hauptverfasser:	SCHIAVI, G. B, BRUNET, S, RIZZI, C. A, LADINSKY, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzimidazoles Biological and medical sciences Bridged Bicyclo Compounds Bridged Bicyclo Compounds, Heterocyclic Caudate Nucleus - metabolism Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Fundamental and applied biological sciences. Psychology Glioma - metabolism GTP-Binding Proteins - metabolism Guinea Pigs Humans In Vitro Techniques Neuroblastoma - metabolism Radioligand Assay Receptors, Serotonin - metabolism Serotonin Antagonists - pharmacokinetics Serotonin Receptor Agonists - pharmacokinetics Swine Tryptamines - pharmacokinetics Tumor Cells, Cultured Vertebrates: nervous system and sense organs
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