Effects of Subchronic Treatment with Trandolapril and Enalapril on Cardiovascular Morphologic Alterations in the Aged Spontaneously Hypertensive Rat with Heart Failure

SUMMARYThe effects of a 3-month treatment period with the angiotensin-converting enzyme (ACE) inhibitors trandolapril (0.3 mg/kg/day, p.o.) and enalapril (10 mg/kg/day, p.o.) on hemodynamics, cardiac hypertrophy, and vascular structures were examined in old spontaneously hypertensive rats (SHRs) (24...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1994, Vol.23 Suppl 4, p.S30-37
Hauptverfasser:	Secchi, J, Lecaque, D, Dunn, F W, Jouquey, S, Auberval, U D, Benzoni, F, Sirugue, O, Hamon, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Angiotensin-Converting Enzyme Inhibitors - therapeutic use Animals Blood Vessels - pathology Body Weight - drug effects Cardiomegaly - drug therapy Enalapril - therapeutic use Heart Failure - drug therapy Heart Failure - pathology Hemodynamics - drug effects Hypertension - drug therapy Hypertension - pathology Indoles - therapeutic use Male Peptidyl-Dipeptidase A - metabolism Rats Rats, Inbred SHR
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