Successful Treatment of Sinusitis Caused by Cunninghamella bertholletiae

Seventeen cases of infections due to Cunninghamella species have been reported worldwide in humans, and there have been only three survivors. We report a case of paranasal sinusitis due to Cunninghamella bertholletiae in an elderly patient who had diabetes mellitus and myelodysplasia. After receivin...

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Veröffentlicht in:	Clinical infectious diseases 1994-08, Vol.19 (2), p.313-316
Hauptverfasser:	Ng, Tony T. C., Campbell, Colin K., Rothera, M., Houghton, J. B., Hughes, D., Denning, David W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amphotericin B - therapeutic use Antifungals Biological and medical sciences Cunninghamella Cunninghamella bertholletiae Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - complications Drug Therapy, Combination Ethmoid Sinusitis - diagnostic imaging Ethmoid Sinusitis - drug therapy Ethmoid Sinusitis - microbiology Fungal infections Fungi Human mycoses Humans Infections Infectious diseases Lungs Male Maxillary Sinusitis - diagnostic imaging Maxillary Sinusitis - drug therapy Maxillary Sinusitis - microbiology Medical sciences Mucorales - isolation & purification Mucormycosis Mucormycosis - complications Mucormycosis - drug therapy Mycoses Mycoses of the respiratory system Myelodysplastic Syndromes - complications Paranasal Sinuses - microbiology Rifampin - therapeutic use Steroid therapy Tomography, X-Ray Computed
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Zusammenfassung:	Seventeen cases of infections due to Cunninghamella species have been reported worldwide in humans, and there have been only three survivors. We report a case of paranasal sinusitis due to Cunninghamella bertholletiae in an elderly patient who had diabetes mellitus and myelodysplasia. After receiving 7 weeks of therapy with deoxycholate amphotericin B (44 mg/kg or a total of 3 g) and rifampin, the patient was cured and did not have to undergo radical surgery.
ISSN:	1058-4838 1537-6591
DOI:	10.1093/clinids/19.2.313