Prolonged Analgesia After Epidural Injection of a Poorly Soluble Salt of Fentanyl

Epidurally administered fentanyl is commonly used in postoperative pain management. The onset of action is rapid, but the duration of analgesia is short. In this study we examined the hypothesis that a poorly soluble salt of fentanyl (fentanyl pamoate) would create a depot of the drug in the epidura...

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Veröffentlicht in:	Anesthesia and analgesia 1994-11, Vol.79 (5), p.905-910
Hauptverfasser:	Randell, Tarja T., Östman, Pontus L. G., Flanagan, Douglas R., Perng, C.-Y., Hrdy, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesia, Epidural Analgesics Animals Biological and medical sciences Dose-Response Relationship, Drug Fentanyl - administration & dosage Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Solubility
Online-Zugang:	Volltext
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