Toluene diisocyanate-induced airway hyperreactivity and pathology in the guinea pig

We assessed the nature and progression of airway mucosal disease and histaminic reactivity in English short-haired guinea pigs at 2, 24, 72, 168, and 504 hours after toluene diisocyanate (TDI) exposure (4 hours of 3 ppm of TDI for 5 consecutive days). To also determine whether TDI-specific, IgE-like...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1986-06, Vol.77 (6), p.828-834
Hauptverfasser:	Cibulas, William, Murlas, Christopher G., Miller, Marian L., Vinegar, Allen, Schmidt, David J., McKay, Roy T., Bernstein, I.Leonard, Brooks, Stuart M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Resistance Animals Biological and medical sciences Bronchial Provocation Tests Cyanates - immunology Experimental and animal immunopathology. Animal models Guinea Pigs Histamine Immunoglobulin E - immunology Immunopathology Male Medical sciences Skin Tests Time Factors Toluene 2,4-Diisocyanate - immunology
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