Defective gamma-interferon production in peripheral blood leukocytes of patients with acute tuberculosis

Production of interferon (IFN)-gamma by peripheral blood leukocytes (PBL) was examined in cultures of unseparated fresh whole blood exposed to phytohemagglutinin (PHA), concanavalin A (Con A), or pokeweed mitogen (PWM). The yield of IFN-gamma was measured by a newly developed immunoradiometric assay...

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Veröffentlicht in:	Journal of clinical immunology 1986-03, Vol.6 (2), p.146-151
Hauptverfasser:	VILCEK, J, KLION, A, HENRIKSEN-DESTEFANO, H, ZEMTSOV, A, DAVIDSON, D. M, DAVIDSON, M, FRIEDMANKIEN, A. E, JUNMING LE
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Bacterial diseases Biological and medical sciences Concanavalin A - pharmacology Female Human bacterial diseases Humans In Vitro Techniques Infectious diseases Interferon-gamma - blood Interleukin-2 - immunology Leukocytes - immunology Male Medical sciences Middle Aged Phytohemagglutinins - pharmacology Pokeweed Mitogens - pharmacology T-Lymphocytes - immunology Tuberculosis and atypical mycobacterial infections Tuberculosis, Pulmonary - immunology
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