Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis

A cDNA clone for the β-chain of human alcohol dehydrogenase (ADH) was used to isolate several cross-hybridizing clones from a mouse liver cDNA library. Clones pADHm9 and a portion of pADHm12 were sequenced. pADHm9 coded for a sequence of 151 C-terminal amino acids and some untranslated sequences fro...

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Veröffentlicht in:	Gene 1986, Vol.41 (2), p.217-224
Hauptverfasser:	Ceci, Jeffrey D., Lawther, Robert, Duester, Gregg, Hatfield, G.Wesley, Smith, Moyra, O'Malley, Mary P., Felder, Michael R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Dehydrogenase Alcohol Oxidoreductases - biosynthesis Alcohol Oxidoreductases - genetics Amino Acid Sequence Animals Base Sequence Biological and medical sciences Biotechnology Cloning, Molecular DNA - analysis DNA Restriction Enzymes Enzyme Induction Female Fundamental and applied biological sciences. Psychology gene cloning Gene expression Genes - drug effects Genetic engineering genetic regulation Genetic technics Humans Kidney - drug effects Kidney - enzymology Kinetics Liver - enzymology liver DNA library Methods. Procedures. Technologies Mice Mice, Inbred A Molecular and cellular biology Molecular cloning Molecular genetics Nucleic Acid Hybridization Protein Biosynthesis Recombinant DNA Sequence Homology, Nucleic Acid Testosterone - pharmacology
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