The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis
Concentrations of plasma triglycerides, cholesterol, total lipids and lipid peroxides in patients with atherosclerotic lesions of peripheral arteries, who were divided into groups according to the extent and intensity of the lesions, were estimated, as well as lipid peroxide levels in the arterial w...
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Veröffentlicht in: | Clinica chimica acta 1986-03, Vol.155 (3), p.275-283 |
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creator | Ledwoż yw, Andrzej Michalak, Jerzy Stȩpień, Adam Ka̧dziołka, Adam |
description | Concentrations of plasma triglycerides, cholesterol, total lipids and lipid peroxides in patients with atherosclerotic lesions of peripheral arteries, who were divided into groups according to the extent and intensity of the lesions, were estimated, as well as lipid peroxide levels in the arterial wall. Statistically highly significant increases of the estimated compounds were found in all groups in comparison with the controls. The existence of a positive correlation between the lipid peroxide concentration and other investigated components in plasma and between the lipid peroxide level in plasma and in the arterial wall was found. Possible mechanisms for lipid peroxide involvement in the process of originating atherosclerotic lesions are discussed. |
doi_str_mv | 10.1016/0009-8981(86)90247-0 |
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Statistically highly significant increases of the estimated compounds were found in all groups in comparison with the controls. The existence of a positive correlation between the lipid peroxide concentration and other investigated components in plasma and between the lipid peroxide level in plasma and in the arterial wall was found. Possible mechanisms for lipid peroxide involvement in the process of originating atherosclerotic lesions are discussed.</description><subject>Adult</subject><subject>Aged</subject><subject>Arteries - metabolism</subject><subject>Arteriosclerosis - blood</subject><subject>Atherosclerosis</subject><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Cholesterol</subject><subject>Cholesterol - blood</subject><subject>Humans</subject><subject>Lipid peroxides</subject><subject>Lipid Peroxides - blood</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>Malondialdehyde - blood</subject><subject>Malondialdehyde - metabolism</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Platelet Aggregation</subject><subject>Total lipids</subject><subject>Triglycerides</subject><subject>Triglycerides - blood</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtu1TAURS1EVW4LfwCSBwgVqSknseM4EyRU8ahUqZMythz7pDFyHtgO0A_gv3F6r-6QiR_a-2xvL0Jel3BVQik-AEBbyFaWF1K8b6HiTQHPyK6UDSsYb6vnZHe0vCBnMf7IVw6iPCWnrAEpa7Ejf-8HpAG9Tm6e4uAW2mH6jTjRxes4apqCe_CPBoOzGC-pGWaPMWGY_SVNc9Keerc4G6me7P5Il6z-cfYpki5htqtJkdo1uOmBDuuoJ6rTkE3R-G118SU56bWP-Oqwn5PvXz7fX38rbu--3lx_ui0Mr6tUiE4wjhw6JhmIRkjeshoqaHRXY9tpYQ0w2WDJdW_AQoWc99iKxvacCy3ZOXm3z82tfq75H2p00aD3esJ5jWqLZLWss5HvjSb3iwF7tQQ36vCoSlAbfbWhVRtaJYV6oq8gj7055K_diPY4dMCd9bcHXUejfR_0ZFw82iSUjWy21z_ubZhZ_HIYVDQOJ4PWBTRJ2dn9v8c_YWKjtw</recordid><startdate>19860328</startdate><enddate>19860328</enddate><creator>Ledwoż;yw, Andrzej</creator><creator>Michalak, Jerzy</creator><creator>Stȩpień, Adam</creator><creator>Ka̧dziołka, Adam</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860328</creationdate><title>The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis</title><author>Ledwoż;yw, Andrzej ; Michalak, Jerzy ; Stȩpień, Adam ; Ka̧dziołka, Adam</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-6b634e40b3830676849350207ab5e9ba6dc0387e14afc0d02e44fe967df446a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Arteries - metabolism</topic><topic>Arteriosclerosis - blood</topic><topic>Atherosclerosis</topic><topic>Atherosclerosis (general aspects, experimental research)</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Cholesterol</topic><topic>Cholesterol - blood</topic><topic>Humans</topic><topic>Lipid peroxides</topic><topic>Lipid Peroxides - blood</topic><topic>Lipids - blood</topic><topic>Male</topic><topic>Malondialdehyde - blood</topic><topic>Malondialdehyde - metabolism</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Platelet Aggregation</topic><topic>Total lipids</topic><topic>Triglycerides</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ledwoż;yw, Andrzej</creatorcontrib><creatorcontrib>Michalak, Jerzy</creatorcontrib><creatorcontrib>Stȩpień, Adam</creatorcontrib><creatorcontrib>Ka̧dziołka, Adam</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ledwoż;yw, Andrzej</au><au>Michalak, Jerzy</au><au>Stȩpień, Adam</au><au>Ka̧dziołka, Adam</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1986-03-28</date><risdate>1986</risdate><volume>155</volume><issue>3</issue><spage>275</spage><epage>283</epage><pages>275-283</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><coden>CCATAR</coden><abstract>Concentrations of plasma triglycerides, cholesterol, total lipids and lipid peroxides in patients with atherosclerotic lesions of peripheral arteries, who were divided into groups according to the extent and intensity of the lesions, were estimated, as well as lipid peroxide levels in the arterial wall. Statistically highly significant increases of the estimated compounds were found in all groups in comparison with the controls. The existence of a positive correlation between the lipid peroxide concentration and other investigated components in plasma and between the lipid peroxide level in plasma and in the arterial wall was found. Possible mechanisms for lipid peroxide involvement in the process of originating atherosclerotic lesions are discussed.</abstract><cop>Shannon</cop><pub>Elsevier B.V</pub><pmid>3708856</pmid><doi>10.1016/0009-8981(86)90247-0</doi><tpages>9</tpages></addata></record> |
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subjects | Adult Aged Arteries - metabolism Arteriosclerosis - blood Atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cholesterol Cholesterol - blood Humans Lipid peroxides Lipid Peroxides - blood Lipids - blood Male Malondialdehyde - blood Malondialdehyde - metabolism Medical sciences Middle Aged Platelet Aggregation Total lipids Triglycerides Triglycerides - blood |
title | The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis |
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