Blood pressure, insulin, and glycemia in nondiabetic subjects
The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A 1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and dias...
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| Veröffentlicht in: | The American journal of medicine 1986-05, Vol.80 (5), p.861-864 |
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| container_issue | 5 |
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| container_title | The American journal of medicine |
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| creator | Fournier, Arthur M. Gadia, Maria T. Kubrusly, Denise B. Skyler, Jay S. Sosenko, Jay M. |
| description | The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A
1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p |
| doi_str_mv | 10.1016/0002-9343(86)90629-7 |
| format | Article |
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1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p <0.01; r = 0.30, p <0.01) and hemoglobin A
1 levels (r = 0.28, p <0.001; r = 0.22, p <0.05) in women. These blood pressure indexes were also related to insulin levels in men (r = 0.23, p <0.05; r = 0.02, p <0.05). In a multiple regression analysis, the association between blood pressure and insulin level was diminished with an allowance for adiposity; however, it remained statistically significant. These data indicate that blood pressure is related to insulin levels in nondiabetic subjects and suggest that insulin may be a physiologic determinant of blood pressure.]]></description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/0002-9343(86)90629-7</identifier><identifier>PMID: 3518437</identifier><identifier>CODEN: AJMEAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Applied sciences ; Biological and medical sciences ; Blood Glucose - analysis ; Blood Pressure ; Endocrine pancreas ; Exact sciences and technology ; Fasting ; Female ; Fundamental and applied biological sciences. Psychology ; Glycated Hemoglobin A - analysis ; Hormones. Régulation ; Humans ; Insulin - blood ; Male ; Other techniques and industries ; Reference Values ; Regression Analysis ; Sex Characteristics ; Vertebrates: endocrinology</subject><ispartof>The American journal of medicine, 1986-05, Vol.80 (5), p.861-864</ispartof><rights>1986</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-1f45aa2148d5ae7b45b7a9d64aa7aeb2e02e08d1c90c952fb85f2999abec53b73</citedby><cites>FETCH-LOGICAL-c415t-1f45aa2148d5ae7b45b7a9d64aa7aeb2e02e08d1c90c952fb85f2999abec53b73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9343(86)90629-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8108819$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8128341$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3518437$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fournier, Arthur M.</creatorcontrib><creatorcontrib>Gadia, Maria T.</creatorcontrib><creatorcontrib>Kubrusly, Denise B.</creatorcontrib><creatorcontrib>Skyler, Jay S.</creatorcontrib><creatorcontrib>Sosenko, Jay M.</creatorcontrib><title>Blood pressure, insulin, and glycemia in nondiabetic subjects</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description><![CDATA[The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A
1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p <0.01; r = 0.30, p <0.01) and hemoglobin A
1 levels (r = 0.28, p <0.001; r = 0.22, p <0.05) in women. These blood pressure indexes were also related to insulin levels in men (r = 0.23, p <0.05; r = 0.02, p <0.05). In a multiple regression analysis, the association between blood pressure and insulin level was diminished with an allowance for adiposity; however, it remained statistically significant. These data indicate that blood pressure is related to insulin levels in nondiabetic subjects and suggest that insulin may be a physiologic determinant of blood pressure.]]></description><subject>Applied sciences</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - analysis</subject><subject>Blood Pressure</subject><subject>Endocrine pancreas</subject><subject>Exact sciences and technology</subject><subject>Fasting</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>Hormones. Régulation</subject><subject>Humans</subject><subject>Insulin - blood</subject><subject>Male</subject><subject>Other techniques and industries</subject><subject>Reference Values</subject><subject>Regression Analysis</subject><subject>Sex Characteristics</subject><subject>Vertebrates: endocrinology</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1LwzAUhoMoc07_gUIvRBRWTdokTS4UdPgFA2_0OqTJqWR07UxaYf_e1I1dKgRCznnynsOD0CnB1wQTfoMxzlKZ0_xS8CuJeSbTYg-NCWMsLQjP9tF4hxyioxAW8Ykl4yM0yhkRNC_G6PahblubrDyE0HuYJq4Jfe2aaaIbm3zWawNLp2M1adrGOl1C50wS-nIBpgvH6KDSdYCT7T1BH0-P77OXdP72_Dq7n6eGEtalpKJM64xQYZmGoqSsLLS0nGpdaCgzwPEIS4zERrKsKgWrMillnGZYXhb5BF1scle-_eohdGrpgoG61g20fVAFFznlVEaQbkDj2xA8VGrl3VL7tSJYDdbUoEQNSpTg6teaGvLPtvl9uQS7-7TVFPvn274ORteV141xYYcJksX55H8MC0GGJe82GERl3w68CsZBY8A6H60q27q_1_0BN9eUrw</recordid><startdate>19860501</startdate><enddate>19860501</enddate><creator>Fournier, Arthur M.</creator><creator>Gadia, Maria T.</creator><creator>Kubrusly, Denise B.</creator><creator>Skyler, Jay S.</creator><creator>Sosenko, Jay M.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860501</creationdate><title>Blood pressure, insulin, and glycemia in nondiabetic subjects</title><author>Fournier, Arthur M. ; Gadia, Maria T. ; Kubrusly, Denise B. ; Skyler, Jay S. ; Sosenko, Jay M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-1f45aa2148d5ae7b45b7a9d64aa7aeb2e02e08d1c90c952fb85f2999abec53b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Applied sciences</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - analysis</topic><topic>Blood Pressure</topic><topic>Endocrine pancreas</topic><topic>Exact sciences and technology</topic><topic>Fasting</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>Hormones. Régulation</topic><topic>Humans</topic><topic>Insulin - blood</topic><topic>Male</topic><topic>Other techniques and industries</topic><topic>Reference Values</topic><topic>Regression Analysis</topic><topic>Sex Characteristics</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fournier, Arthur M.</creatorcontrib><creatorcontrib>Gadia, Maria T.</creatorcontrib><creatorcontrib>Kubrusly, Denise B.</creatorcontrib><creatorcontrib>Skyler, Jay S.</creatorcontrib><creatorcontrib>Sosenko, Jay M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fournier, Arthur M.</au><au>Gadia, Maria T.</au><au>Kubrusly, Denise B.</au><au>Skyler, Jay S.</au><au>Sosenko, Jay M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood pressure, insulin, and glycemia in nondiabetic subjects</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>1986-05-01</date><risdate>1986</risdate><volume>80</volume><issue>5</issue><spage>861</spage><epage>864</epage><pages>861-864</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><coden>AJMEAZ</coden><abstract><![CDATA[The relation of blood pressure to fasting (basal) insulin and glycosylated hemoglobin (hemoglobin A
1) was examined in 248 nondiabetic subjects (137 women and 111 men). None of the subjects was taking antihypertensive medication. There were statistically significant associations of systolic and diastolic blood pressure with insulin levels (r = 0.24, p <0.01; r = 0.30, p <0.01) and hemoglobin A
1 levels (r = 0.28, p <0.001; r = 0.22, p <0.05) in women. These blood pressure indexes were also related to insulin levels in men (r = 0.23, p <0.05; r = 0.02, p <0.05). In a multiple regression analysis, the association between blood pressure and insulin level was diminished with an allowance for adiposity; however, it remained statistically significant. These data indicate that blood pressure is related to insulin levels in nondiabetic subjects and suggest that insulin may be a physiologic determinant of blood pressure.]]></abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3518437</pmid><doi>10.1016/0002-9343(86)90629-7</doi><tpages>4</tpages></addata></record> |
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| ispartof | The American journal of medicine, 1986-05, Vol.80 (5), p.861-864 |
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| subjects | Applied sciences Biological and medical sciences Blood Glucose - analysis Blood Pressure Endocrine pancreas Exact sciences and technology Fasting Female Fundamental and applied biological sciences. Psychology Glycated Hemoglobin A - analysis Hormones. Régulation Humans Insulin - blood Male Other techniques and industries Reference Values Regression Analysis Sex Characteristics Vertebrates: endocrinology |
| title | Blood pressure, insulin, and glycemia in nondiabetic subjects |
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