Giant axonal neuropathy: Central abnormalities demonstrated by evoked potentials
Previous studies of giant axonal neuropathy have reported clinical and pathological findings that indicate involvement of the central nervous system. We studied 3 boys with giant axonal neuropathy, who were 14 to 16 years of age, using auditory, visual, and somatosensory evoked potentials. Absence o...
Gespeichert in:
| Veröffentlicht in: | Annals of neurology 1986-04, Vol.19 (4), p.394-396 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 396 |
|---|---|
| container_issue | 4 |
| container_start_page | 394 |
| container_title | Annals of neurology |
| container_volume | 19 |
| creator | Majnemer, Annette Rosenblatt, Bernard Watters, Gordon Andermann, Frederick |
| description | Previous studies of giant axonal neuropathy have reported clinical and pathological findings that indicate involvement of the central nervous system. We studied 3 boys with giant axonal neuropathy, who were 14 to 16 years of age, using auditory, visual, and somatosensory evoked potentials. Absence of waveforms and prolongation of peak and interwave latencies were found. Abnormalities were noted in all modalities. The auditory brainstem evoked response in particular indicated a significant increase in brainstem conduction time. These studies add clinical neurophysiological confirmation of the central nervous system involvement in this disorder and may also provide a means of quantitative evaluation of its progression. |
| doi_str_mv | 10.1002/ana.410190417 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76833433</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76833433</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4987-4aee6c082ced489e01140ae3fd93b70b58e036447f0a873ba9e7cb5e34b8f45e3</originalsourceid><addsrcrecordid>eNp9kEFP3DAQha2qiC7QY4-Vcqh6C4zXTuxwWy2wUCHKoVV7sybJRDUk9tbOAvvvMdpo1VNPz5r3zfjpMfaJwykHmJ-hw1PJgVcguXrHZrwQPNdzWb1nMxClzAsu5Ad2FOMDAFQlh0N2KICDhvmM3a8sujHDF--wzxxtgl_j-Gd7ni3JjSHNsHY-DNjb0VLMWhq8i8kYqc3qbUZP_jG91n5MuMU-nrCDLgl9nPSY_by6_LG8zm-_r26Wi9u8kZVWuUSisgE9b6iVuiLgXAKS6NpK1ArqQtNbeKk6QK1EjRWppi5IyFp3Mukx-7q7uw7-74biaAYbG-p7dOQ30ahSCyGFSGC-A5vgYwzUmXWwA4at4WDeGjSpQbNvMPGfp8ObeqB2T0-VJf_L5GNssO8CusbGPaY18AJ0wtQOe7Y9bf__p1ncLf4NMAW2caSX_SaGR1MqoQrz625ltLi4EOr3N6PEK3aVmH8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76833433</pqid></control><display><type>article</type><title>Giant axonal neuropathy: Central abnormalities demonstrated by evoked potentials</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Majnemer, Annette ; Rosenblatt, Bernard ; Watters, Gordon ; Andermann, Frederick</creator><creatorcontrib>Majnemer, Annette ; Rosenblatt, Bernard ; Watters, Gordon ; Andermann, Frederick</creatorcontrib><description>Previous studies of giant axonal neuropathy have reported clinical and pathological findings that indicate involvement of the central nervous system. We studied 3 boys with giant axonal neuropathy, who were 14 to 16 years of age, using auditory, visual, and somatosensory evoked potentials. Absence of waveforms and prolongation of peak and interwave latencies were found. Abnormalities were noted in all modalities. The auditory brainstem evoked response in particular indicated a significant increase in brainstem conduction time. These studies add clinical neurophysiological confirmation of the central nervous system involvement in this disorder and may also provide a means of quantitative evaluation of its progression.</description><identifier>ISSN: 0364-5134</identifier><identifier>EISSN: 1531-8249</identifier><identifier>DOI: 10.1002/ana.410190417</identifier><identifier>PMID: 3010802</identifier><identifier>CODEN: ANNED3</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Biological and medical sciences ; Brain Stem - physiopathology ; Central Nervous System - physiopathology ; Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction ; Evoked Potentials, Auditory ; Evoked Potentials, Somatosensory ; Evoked Potentials, Visual ; Humans ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Peripheral Nervous System Diseases - physiopathology</subject><ispartof>Annals of neurology, 1986-04, Vol.19 (4), p.394-396</ispartof><rights>Copyright © 1986 American Neurological Association</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4987-4aee6c082ced489e01140ae3fd93b70b58e036447f0a873ba9e7cb5e34b8f45e3</citedby><cites>FETCH-LOGICAL-c4987-4aee6c082ced489e01140ae3fd93b70b58e036447f0a873ba9e7cb5e34b8f45e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fana.410190417$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fana.410190417$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8801508$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3010802$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Majnemer, Annette</creatorcontrib><creatorcontrib>Rosenblatt, Bernard</creatorcontrib><creatorcontrib>Watters, Gordon</creatorcontrib><creatorcontrib>Andermann, Frederick</creatorcontrib><title>Giant axonal neuropathy: Central abnormalities demonstrated by evoked potentials</title><title>Annals of neurology</title><addtitle>Ann Neurol</addtitle><description>Previous studies of giant axonal neuropathy have reported clinical and pathological findings that indicate involvement of the central nervous system. We studied 3 boys with giant axonal neuropathy, who were 14 to 16 years of age, using auditory, visual, and somatosensory evoked potentials. Absence of waveforms and prolongation of peak and interwave latencies were found. Abnormalities were noted in all modalities. The auditory brainstem evoked response in particular indicated a significant increase in brainstem conduction time. These studies add clinical neurophysiological confirmation of the central nervous system involvement in this disorder and may also provide a means of quantitative evaluation of its progression.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Brain Stem - physiopathology</subject><subject>Central Nervous System - physiopathology</subject><subject>Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction</subject><subject>Evoked Potentials, Auditory</subject><subject>Evoked Potentials, Somatosensory</subject><subject>Evoked Potentials, Visual</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Peripheral Nervous System Diseases - physiopathology</subject><issn>0364-5134</issn><issn>1531-8249</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFP3DAQha2qiC7QY4-Vcqh6C4zXTuxwWy2wUCHKoVV7sybJRDUk9tbOAvvvMdpo1VNPz5r3zfjpMfaJwykHmJ-hw1PJgVcguXrHZrwQPNdzWb1nMxClzAsu5Ad2FOMDAFQlh0N2KICDhvmM3a8sujHDF--wzxxtgl_j-Gd7ni3JjSHNsHY-DNjb0VLMWhq8i8kYqc3qbUZP_jG91n5MuMU-nrCDLgl9nPSY_by6_LG8zm-_r26Wi9u8kZVWuUSisgE9b6iVuiLgXAKS6NpK1ArqQtNbeKk6QK1EjRWppi5IyFp3Mukx-7q7uw7-74biaAYbG-p7dOQ30ahSCyGFSGC-A5vgYwzUmXWwA4at4WDeGjSpQbNvMPGfp8ObeqB2T0-VJf_L5GNssO8CusbGPaY18AJ0wtQOe7Y9bf__p1ncLf4NMAW2caSX_SaGR1MqoQrz625ltLi4EOr3N6PEK3aVmH8</recordid><startdate>198604</startdate><enddate>198604</enddate><creator>Majnemer, Annette</creator><creator>Rosenblatt, Bernard</creator><creator>Watters, Gordon</creator><creator>Andermann, Frederick</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Willey-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198604</creationdate><title>Giant axonal neuropathy: Central abnormalities demonstrated by evoked potentials</title><author>Majnemer, Annette ; Rosenblatt, Bernard ; Watters, Gordon ; Andermann, Frederick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4987-4aee6c082ced489e01140ae3fd93b70b58e036447f0a873ba9e7cb5e34b8f45e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Brain Stem - physiopathology</topic><topic>Central Nervous System - physiopathology</topic><topic>Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction</topic><topic>Evoked Potentials, Auditory</topic><topic>Evoked Potentials, Somatosensory</topic><topic>Evoked Potentials, Visual</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Peripheral Nervous System Diseases - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Majnemer, Annette</creatorcontrib><creatorcontrib>Rosenblatt, Bernard</creatorcontrib><creatorcontrib>Watters, Gordon</creatorcontrib><creatorcontrib>Andermann, Frederick</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Majnemer, Annette</au><au>Rosenblatt, Bernard</au><au>Watters, Gordon</au><au>Andermann, Frederick</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Giant axonal neuropathy: Central abnormalities demonstrated by evoked potentials</atitle><jtitle>Annals of neurology</jtitle><addtitle>Ann Neurol</addtitle><date>1986-04</date><risdate>1986</risdate><volume>19</volume><issue>4</issue><spage>394</spage><epage>396</epage><pages>394-396</pages><issn>0364-5134</issn><eissn>1531-8249</eissn><coden>ANNED3</coden><abstract>Previous studies of giant axonal neuropathy have reported clinical and pathological findings that indicate involvement of the central nervous system. We studied 3 boys with giant axonal neuropathy, who were 14 to 16 years of age, using auditory, visual, and somatosensory evoked potentials. Absence of waveforms and prolongation of peak and interwave latencies were found. Abnormalities were noted in all modalities. The auditory brainstem evoked response in particular indicated a significant increase in brainstem conduction time. These studies add clinical neurophysiological confirmation of the central nervous system involvement in this disorder and may also provide a means of quantitative evaluation of its progression.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>3010802</pmid><doi>10.1002/ana.410190417</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0364-5134 |
| ispartof | Annals of neurology, 1986-04, Vol.19 (4), p.394-396 |
| issn | 0364-5134 1531-8249 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76833433 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Biological and medical sciences Brain Stem - physiopathology Central Nervous System - physiopathology Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction Evoked Potentials, Auditory Evoked Potentials, Somatosensory Evoked Potentials, Visual Humans Male Medical sciences Nervous system (semeiology, syndromes) Neurology Peripheral Nervous System Diseases - physiopathology |
| title | Giant axonal neuropathy: Central abnormalities demonstrated by evoked potentials |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T19%3A27%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Giant%20axonal%20neuropathy:%20Central%20abnormalities%20demonstrated%20by%20evoked%20potentials&rft.jtitle=Annals%20of%20neurology&rft.au=Majnemer,%20Annette&rft.date=1986-04&rft.volume=19&rft.issue=4&rft.spage=394&rft.epage=396&rft.pages=394-396&rft.issn=0364-5134&rft.eissn=1531-8249&rft.coden=ANNED3&rft_id=info:doi/10.1002/ana.410190417&rft_dat=%3Cproquest_cross%3E76833433%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76833433&rft_id=info:pmid/3010802&rfr_iscdi=true |