Taxol Content of Stored Fresh and Dried Taxus Clippings
The taxol content of dried Taxus biomass was monitored monthly for 15 months. Intact and finely ground biomass was stored at room temperature (22 degrees-24 degrees) as well as under refrigeration (2 degrees-4 degrees). In addition, intact fresh clippings stored under refrigeration in sealed plastic...
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| Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 1994-07, Vol.57 (7), p.1025-1028 |
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| container_end_page | 1028 |
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| container_issue | 7 |
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| container_title | Journal of natural products (Washington, D.C.) |
| container_volume | 57 |
| creator | ElSohly, Hala N Croom, Edward M El-Kashoury, ElSayeda ElSohly, Mahmoud A McChesney, James D |
| description | The taxol content of dried Taxus biomass was monitored monthly for 15 months. Intact and finely ground biomass was stored at room temperature (22 degrees-24 degrees) as well as under refrigeration (2 degrees-4 degrees). In addition, intact fresh clippings stored under refrigeration in sealed plastic bags for up to 10 weeks were evaluated for changes in taxol content. Analysis indicates that properly dried Taxus clippings can be stored either intact or powdered at room temperature or under refrigeration with no apparent loss of taxol content. The taxol content in fresh intact clippings was also stable for at least 10 weeks when stored under refrigeration. |
| doi_str_mv | 10.1021/np50109a027 |
| format | Article |
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Intact and finely ground biomass was stored at room temperature (22 degrees-24 degrees) as well as under refrigeration (2 degrees-4 degrees). In addition, intact fresh clippings stored under refrigeration in sealed plastic bags for up to 10 weeks were evaluated for changes in taxol content. Analysis indicates that properly dried Taxus clippings can be stored either intact or powdered at room temperature or under refrigeration with no apparent loss of taxol content. The taxol content in fresh intact clippings was also stable for at least 10 weeks when stored under refrigeration.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np50109a027</identifier><identifier>PMID: 7964784</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>ALCALOIDE ; ALCALOIDES ; ALKALOIDS ; ALMACENAMIENTO EN FRIGORIFICOS ; ANALISIS CUANTITATIVO ; ANALYSE QUANTITATIVE ; APTITUD PARA LA CONSERVACION ; APTITUDE A LA CONSERVATION ; BARK PRODUCTS ; Biomass ; CHEMICAL COMPOSITION ; Chromatography, High Pressure Liquid ; COMPOSICION QUIMICA ; COMPOSITION CHIMIQUE ; CORTE ; CUTTING ; DECOUPAGE ; DEHYDRATION ; DESHIDRATACION ; DESHYDRATATION ; KEEPING QUALITY ; Paclitaxel - analogs & derivatives ; Paclitaxel - chemistry ; Paclitaxel - isolation & purification ; Plant Leaves - chemistry ; Plants, Medicinal - chemistry ; PRODUIT A BASE D'ECORCE ; QUANTITATIVE ANALYSIS ; REFRIGERATED STORAGE ; Refrigeration ; STEMS ; STOCKAGE AU FROID ; STORAGE QUALITY ; TALLO ; TAXUS ; TAXUS BREVIFOLIA ; TEMPERATURA ; TEMPERATURE ; TIGE ; TROZOS DE CORTEZA</subject><ispartof>Journal of natural products (Washington, D.C.), 1994-07, Vol.57 (7), p.1025-1028</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a404t-9d9cb05e0a2a5fce8159e78d7c4cda6cdb46713ce782a38fcd490a91d5edd4593</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/np50109a027$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/np50109a027$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,2763,27074,27922,27923,56736,56786</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7964784$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ElSohly, Hala N</creatorcontrib><creatorcontrib>Croom, Edward M</creatorcontrib><creatorcontrib>El-Kashoury, ElSayeda</creatorcontrib><creatorcontrib>ElSohly, Mahmoud A</creatorcontrib><creatorcontrib>McChesney, James D</creatorcontrib><title>Taxol Content of Stored Fresh and Dried Taxus Clippings</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>The taxol content of dried Taxus biomass was monitored monthly for 15 months. Intact and finely ground biomass was stored at room temperature (22 degrees-24 degrees) as well as under refrigeration (2 degrees-4 degrees). In addition, intact fresh clippings stored under refrigeration in sealed plastic bags for up to 10 weeks were evaluated for changes in taxol content. Analysis indicates that properly dried Taxus clippings can be stored either intact or powdered at room temperature or under refrigeration with no apparent loss of taxol content. The taxol content in fresh intact clippings was also stable for at least 10 weeks when stored under refrigeration.</description><subject>ALCALOIDE</subject><subject>ALCALOIDES</subject><subject>ALKALOIDS</subject><subject>ALMACENAMIENTO EN FRIGORIFICOS</subject><subject>ANALISIS CUANTITATIVO</subject><subject>ANALYSE QUANTITATIVE</subject><subject>APTITUD PARA LA CONSERVACION</subject><subject>APTITUDE A LA CONSERVATION</subject><subject>BARK PRODUCTS</subject><subject>Biomass</subject><subject>CHEMICAL COMPOSITION</subject><subject>Chromatography, High Pressure Liquid</subject><subject>COMPOSICION QUIMICA</subject><subject>COMPOSITION CHIMIQUE</subject><subject>CORTE</subject><subject>CUTTING</subject><subject>DECOUPAGE</subject><subject>DEHYDRATION</subject><subject>DESHIDRATACION</subject><subject>DESHYDRATATION</subject><subject>KEEPING QUALITY</subject><subject>Paclitaxel - analogs & derivatives</subject><subject>Paclitaxel - chemistry</subject><subject>Paclitaxel - isolation & purification</subject><subject>Plant Leaves - chemistry</subject><subject>Plants, Medicinal - chemistry</subject><subject>PRODUIT A BASE D'ECORCE</subject><subject>QUANTITATIVE ANALYSIS</subject><subject>REFRIGERATED STORAGE</subject><subject>Refrigeration</subject><subject>STEMS</subject><subject>STOCKAGE AU FROID</subject><subject>STORAGE QUALITY</subject><subject>TALLO</subject><subject>TAXUS</subject><subject>TAXUS BREVIFOLIA</subject><subject>TEMPERATURA</subject><subject>TEMPERATURE</subject><subject>TIGE</subject><subject>TROZOS DE CORTEZA</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1r3DAQhkVo2G43OfVWKPiUHoLTkfV9LJtPCKSwu5dchFaSt069livZkPz7KHgJPRR6GmaehxnpRegzhgsMFf7e9QwwKAOVOEJzzCooOVTsA5oD5qQkktOP6FNKTwBAQLEZmgnFqZB0jsTaPIe2WIZu8N1QhLpYDSF6V1xHn34VpnPFZWxyn70xFcu26fum26UTdFybNvnTQ12gzfXVenlb3j_c3C1_3JeGAh1K5ZTdAvNgKsNq6yVmygvphKXWGW7dlnKBic2zyhBZW0cVGIUd885RpsgCnU17-xj-jD4Net8k69vWdD6MSQsuK6mI_K-I85386yqL55NoY0gp-lr3sdmb-KIx6Lc89V95ZvvrYe243Xv37h4CzLyceJMG__yOTfytuSCC6fXPlb6hq8tHKrF-879Mfm2CNrvYJL1ZKYaZ5CTDbxM0NumnMMYuR_vPZ70CXymSrA</recordid><startdate>19940701</startdate><enddate>19940701</enddate><creator>ElSohly, Hala N</creator><creator>Croom, Edward M</creator><creator>El-Kashoury, ElSayeda</creator><creator>ElSohly, Mahmoud A</creator><creator>McChesney, James D</creator><general>American Chemical Society</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19940701</creationdate><title>Taxol Content of Stored Fresh and Dried Taxus Clippings</title><author>ElSohly, Hala N ; Croom, Edward M ; El-Kashoury, ElSayeda ; ElSohly, Mahmoud A ; McChesney, James D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a404t-9d9cb05e0a2a5fce8159e78d7c4cda6cdb46713ce782a38fcd490a91d5edd4593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>ALCALOIDE</topic><topic>ALCALOIDES</topic><topic>ALKALOIDS</topic><topic>ALMACENAMIENTO EN FRIGORIFICOS</topic><topic>ANALISIS CUANTITATIVO</topic><topic>ANALYSE QUANTITATIVE</topic><topic>APTITUD PARA LA CONSERVACION</topic><topic>APTITUDE A LA CONSERVATION</topic><topic>BARK PRODUCTS</topic><topic>Biomass</topic><topic>CHEMICAL COMPOSITION</topic><topic>Chromatography, High Pressure Liquid</topic><topic>COMPOSICION QUIMICA</topic><topic>COMPOSITION CHIMIQUE</topic><topic>CORTE</topic><topic>CUTTING</topic><topic>DECOUPAGE</topic><topic>DEHYDRATION</topic><topic>DESHIDRATACION</topic><topic>DESHYDRATATION</topic><topic>KEEPING QUALITY</topic><topic>Paclitaxel - analogs & derivatives</topic><topic>Paclitaxel - chemistry</topic><topic>Paclitaxel - isolation & purification</topic><topic>Plant Leaves - chemistry</topic><topic>Plants, Medicinal - chemistry</topic><topic>PRODUIT A BASE D'ECORCE</topic><topic>QUANTITATIVE ANALYSIS</topic><topic>REFRIGERATED STORAGE</topic><topic>Refrigeration</topic><topic>STEMS</topic><topic>STOCKAGE AU FROID</topic><topic>STORAGE QUALITY</topic><topic>TALLO</topic><topic>TAXUS</topic><topic>TAXUS BREVIFOLIA</topic><topic>TEMPERATURA</topic><topic>TEMPERATURE</topic><topic>TIGE</topic><topic>TROZOS DE CORTEZA</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ElSohly, Hala N</creatorcontrib><creatorcontrib>Croom, Edward M</creatorcontrib><creatorcontrib>El-Kashoury, ElSayeda</creatorcontrib><creatorcontrib>ElSohly, Mahmoud A</creatorcontrib><creatorcontrib>McChesney, James D</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ElSohly, Hala N</au><au>Croom, Edward M</au><au>El-Kashoury, ElSayeda</au><au>ElSohly, Mahmoud A</au><au>McChesney, James D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Taxol Content of Stored Fresh and Dried Taxus Clippings</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>1994-07-01</date><risdate>1994</risdate><volume>57</volume><issue>7</issue><spage>1025</spage><epage>1028</epage><pages>1025-1028</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><abstract>The taxol content of dried Taxus biomass was monitored monthly for 15 months. Intact and finely ground biomass was stored at room temperature (22 degrees-24 degrees) as well as under refrigeration (2 degrees-4 degrees). In addition, intact fresh clippings stored under refrigeration in sealed plastic bags for up to 10 weeks were evaluated for changes in taxol content. Analysis indicates that properly dried Taxus clippings can be stored either intact or powdered at room temperature or under refrigeration with no apparent loss of taxol content. The taxol content in fresh intact clippings was also stable for at least 10 weeks when stored under refrigeration.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>7964784</pmid><doi>10.1021/np50109a027</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0163-3864 |
| ispartof | Journal of natural products (Washington, D.C.), 1994-07, Vol.57 (7), p.1025-1028 |
| issn | 0163-3864 1520-6025 |
| language | eng |
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| source | MEDLINE; ACS Publications |
| subjects | ALCALOIDE ALCALOIDES ALKALOIDS ALMACENAMIENTO EN FRIGORIFICOS ANALISIS CUANTITATIVO ANALYSE QUANTITATIVE APTITUD PARA LA CONSERVACION APTITUDE A LA CONSERVATION BARK PRODUCTS Biomass CHEMICAL COMPOSITION Chromatography, High Pressure Liquid COMPOSICION QUIMICA COMPOSITION CHIMIQUE CORTE CUTTING DECOUPAGE DEHYDRATION DESHIDRATACION DESHYDRATATION KEEPING QUALITY Paclitaxel - analogs & derivatives Paclitaxel - chemistry Paclitaxel - isolation & purification Plant Leaves - chemistry Plants, Medicinal - chemistry PRODUIT A BASE D'ECORCE QUANTITATIVE ANALYSIS REFRIGERATED STORAGE Refrigeration STEMS STOCKAGE AU FROID STORAGE QUALITY TALLO TAXUS TAXUS BREVIFOLIA TEMPERATURA TEMPERATURE TIGE TROZOS DE CORTEZA |
| title | Taxol Content of Stored Fresh and Dried Taxus Clippings |
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