In Vivo Activity Of Interferon-γ In Combination With Amphotericin B In The Treatment Of Experimental Cryptococcosis

The effect of recombinant interferon-ã (rIFN-ã) on Cryptococcus neoformans infection was investigated in vivo. BALB/c mice were injected intravenously with 2 'd7 106 C. neoformans. rIFN-ã alone (10 µg intraperitoneally 18 h before, at, and 24 h after infection) significantly increased the survi...

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Veröffentlicht in:	The Journal of infectious diseases 1994-11, Vol.170 (5), p.1331-1334
Hauptverfasser:	Joly, Véronique, Saint-Julien, Line, Carbon, Claude, Yeni, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Amphotericin B - administration & dosage Animals Antifungals Concise Communications Cryptococcosis Cryptococcosis - drug therapy Dosage Drug Therapy, Combination Infections Interferon-gamma - administration & dosage Interferons Macrophages Male Mice Mice, Inbred BALB C Recombinant Proteins Spleen Tumor Necrosis Factor-alpha - analysis Tumors
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