Cyclic GMP-sensitive conductance of retinal rods consists of aqueous pores

The surface membrane of retinal rod and cone outer segments contains a cation-selective conductance which is activated by 3′,5′-cyclic guanosine monophosphate (cGMP) 1–4 . Reduction of this conductance by a light-induced decrease in the cytoplasmic concentration of cGMP appears to generate the elect...

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Veröffentlicht in:	Nature (London) 1986-05, Vol.321 (6065), p.70-72
Hauptverfasser:	Zimmerman, A. L, Baylor, D. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cations Cell physiology Conductance cyclic GMP Cyclic GMP - pharmacology Electric Conductivity Eyes & eyesight Fundamental and applied biological sciences. Psychology Humanities and Social Sciences In Vitro Techniques Ion Channels - drug effects Ion Channels - physiology Ion transport letter membrane currents Membrane Potentials - drug effects Molecular and cellular biology multidisciplinary Necturus Photoreceptor Cells - physiology Pores retina Rod Cell Outer Segment - drug effects Rod Cell Outer Segment - physiology rod outer segment membranes Science Science (multidisciplinary) Urodela Vision, photoreception
Online-Zugang:	Volltext
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