Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron

Purpose : We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. Methods and Materials : The microtron is equipped with a multi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 1994-11, Vol.30 (4), p.971-978
Hauptverfasser: Mageras, G.S., Fuks, Z., O'Brien, J., Brewster, L.J., Burman, C., Chui, C.S., Leibel, S.A., Ling, C.C., Masterson, M.E., Mohan, R., Kutcher, G.J.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 978
container_issue 4
container_start_page 971
container_title International journal of radiation oncology, biology, physics
container_volume 30
creator Mageras, G.S.
Fuks, Z.
O'Brien, J.
Brewster, L.J.
Burman, C.
Chui, C.S.
Leibel, S.A.
Ling, C.C.
Masterson, M.E.
Mohan, R.
Kutcher, G.J.
description Purpose : We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. Methods and Materials : The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance. Results : Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months. Conclusion : Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.
doi_str_mv 10.1016/0360-3016(94)90374-3
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76815248</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0360301694903743</els_id><sourcerecordid>76815248</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</originalsourceid><addsrcrecordid>eNp9kU2P1SAUhonRjHdG_4EmLIzRRfVQSj82Jmbi6CRj3KhxRygcHEwLFag6iT9eeu_NXbriAA8vhwdCnjB4xYC1r4G3UPFSvRialwPwrqn4PbJjfTdUXIhv98nuhDwk5yn9AADGuuaMnHVDy8pkR_5ee5edmqienHe6FPhnwejQa6S_Xb6lOszLmjFWOvgcwzShKWvehjgXOirjQr7FqJY7GiwtJV1iSFllpGty_jtVVED1Eb_SGc3-htnpGEqUf0QeWDUlfHwcL8iXq3efLz9UN5_eX1--vak079tcaRBcDTUgH5UAy4xqTD2OlndWjRpGxWuDYGAUpmeWaVA1A1E3iom2E8j5BXl-yC2d_VwxZTm7pHGalMewJtm1PSt8X8DmAJYGU4po5RLdrOKdZCA36XIzKjejcmjkXrrc8p8e89exPPJ06Gi57D877qtUBNiovHbphHHOGtZvMW8OGBYXvxxGmfT-I4yLqLM0wf2_j38klZ_g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76815248</pqid></control><display><type>article</type><title>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Mageras, G.S. ; Fuks, Z. ; O'Brien, J. ; Brewster, L.J. ; Burman, C. ; Chui, C.S. ; Leibel, S.A. ; Ling, C.C. ; Masterson, M.E. ; Mohan, R. ; Kutcher, G.J.</creator><creatorcontrib>Mageras, G.S. ; Fuks, Z. ; O'Brien, J. ; Brewster, L.J. ; Burman, C. ; Chui, C.S. ; Leibel, S.A. ; Ling, C.C. ; Masterson, M.E. ; Mohan, R. ; Kutcher, G.J.</creatorcontrib><description>Purpose : We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. Methods and Materials : The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance. Results : Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months. Conclusion : Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/0360-3016(94)90374-3</identifier><identifier>PMID: 7961001</identifier><identifier>CODEN: IOBPD3</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Computer-controlled therapy ; Conformal radiotherapy ; Diseases of the urinary system ; Humans ; Male ; Medical sciences ; Multileaf collimator ; Prostate ; Prostatic Neoplasms - radiotherapy ; Radiotherapy Dosage ; Radiotherapy, Computer-Assisted - instrumentation ; Radiotherapy, Computer-Assisted - methods ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Reproducibility of Results ; Software</subject><ispartof>International journal of radiation oncology, biology, physics, 1994-11, Vol.30 (4), p.971-978</ispartof><rights>1994</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</citedby><cites>FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0360-3016(94)90374-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>310,311,315,781,785,790,791,3551,23935,23936,25145,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=3314183$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7961001$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mageras, G.S.</creatorcontrib><creatorcontrib>Fuks, Z.</creatorcontrib><creatorcontrib>O'Brien, J.</creatorcontrib><creatorcontrib>Brewster, L.J.</creatorcontrib><creatorcontrib>Burman, C.</creatorcontrib><creatorcontrib>Chui, C.S.</creatorcontrib><creatorcontrib>Leibel, S.A.</creatorcontrib><creatorcontrib>Ling, C.C.</creatorcontrib><creatorcontrib>Masterson, M.E.</creatorcontrib><creatorcontrib>Mohan, R.</creatorcontrib><creatorcontrib>Kutcher, G.J.</creatorcontrib><title>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</title><title>International journal of radiation oncology, biology, physics</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Purpose : We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. Methods and Materials : The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance. Results : Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months. Conclusion : Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.</description><subject>Biological and medical sciences</subject><subject>Computer-controlled therapy</subject><subject>Conformal radiotherapy</subject><subject>Diseases of the urinary system</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Multileaf collimator</subject><subject>Prostate</subject><subject>Prostatic Neoplasms - radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy, Computer-Assisted - instrumentation</subject><subject>Radiotherapy, Computer-Assisted - methods</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Reproducibility of Results</subject><subject>Software</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2P1SAUhonRjHdG_4EmLIzRRfVQSj82Jmbi6CRj3KhxRygcHEwLFag6iT9eeu_NXbriAA8vhwdCnjB4xYC1r4G3UPFSvRialwPwrqn4PbJjfTdUXIhv98nuhDwk5yn9AADGuuaMnHVDy8pkR_5ee5edmqienHe6FPhnwejQa6S_Xb6lOszLmjFWOvgcwzShKWvehjgXOirjQr7FqJY7GiwtJV1iSFllpGty_jtVVED1Eb_SGc3-htnpGEqUf0QeWDUlfHwcL8iXq3efLz9UN5_eX1--vak079tcaRBcDTUgH5UAy4xqTD2OlndWjRpGxWuDYGAUpmeWaVA1A1E3iom2E8j5BXl-yC2d_VwxZTm7pHGalMewJtm1PSt8X8DmAJYGU4po5RLdrOKdZCA36XIzKjejcmjkXrrc8p8e89exPPJ06Gi57D877qtUBNiovHbphHHOGtZvMW8OGBYXvxxGmfT-I4yLqLM0wf2_j38klZ_g</recordid><startdate>19941115</startdate><enddate>19941115</enddate><creator>Mageras, G.S.</creator><creator>Fuks, Z.</creator><creator>O'Brien, J.</creator><creator>Brewster, L.J.</creator><creator>Burman, C.</creator><creator>Chui, C.S.</creator><creator>Leibel, S.A.</creator><creator>Ling, C.C.</creator><creator>Masterson, M.E.</creator><creator>Mohan, R.</creator><creator>Kutcher, G.J.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19941115</creationdate><title>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</title><author>Mageras, G.S. ; Fuks, Z. ; O'Brien, J. ; Brewster, L.J. ; Burman, C. ; Chui, C.S. ; Leibel, S.A. ; Ling, C.C. ; Masterson, M.E. ; Mohan, R. ; Kutcher, G.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Biological and medical sciences</topic><topic>Computer-controlled therapy</topic><topic>Conformal radiotherapy</topic><topic>Diseases of the urinary system</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Multileaf collimator</topic><topic>Prostate</topic><topic>Prostatic Neoplasms - radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy, Computer-Assisted - instrumentation</topic><topic>Radiotherapy, Computer-Assisted - methods</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Reproducibility of Results</topic><topic>Software</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mageras, G.S.</creatorcontrib><creatorcontrib>Fuks, Z.</creatorcontrib><creatorcontrib>O'Brien, J.</creatorcontrib><creatorcontrib>Brewster, L.J.</creatorcontrib><creatorcontrib>Burman, C.</creatorcontrib><creatorcontrib>Chui, C.S.</creatorcontrib><creatorcontrib>Leibel, S.A.</creatorcontrib><creatorcontrib>Ling, C.C.</creatorcontrib><creatorcontrib>Masterson, M.E.</creatorcontrib><creatorcontrib>Mohan, R.</creatorcontrib><creatorcontrib>Kutcher, G.J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mageras, G.S.</au><au>Fuks, Z.</au><au>O'Brien, J.</au><au>Brewster, L.J.</au><au>Burman, C.</au><au>Chui, C.S.</au><au>Leibel, S.A.</au><au>Ling, C.C.</au><au>Masterson, M.E.</au><au>Mohan, R.</au><au>Kutcher, G.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>1994-11-15</date><risdate>1994</risdate><volume>30</volume><issue>4</issue><spage>971</spage><epage>978</epage><pages>971-978</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><coden>IOBPD3</coden><abstract>Purpose : We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. Methods and Materials : The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance. Results : Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months. Conclusion : Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7961001</pmid><doi>10.1016/0360-3016(94)90374-3</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0360-3016
ispartof International journal of radiation oncology, biology, physics, 1994-11, Vol.30 (4), p.971-978
issn 0360-3016
1879-355X
language eng
recordid cdi_proquest_miscellaneous_76815248
source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Biological and medical sciences
Computer-controlled therapy
Conformal radiotherapy
Diseases of the urinary system
Humans
Male
Medical sciences
Multileaf collimator
Prostate
Prostatic Neoplasms - radiotherapy
Radiotherapy Dosage
Radiotherapy, Computer-Assisted - instrumentation
Radiotherapy, Computer-Assisted - methods
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Reproducibility of Results
Software
title Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T13%3A11%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Initial%20clinical%20experience%20with%20computer-controlled%20conformal%20radiotherapy%20of%20the%20prostate%20using%20a%2050-MeV%20medical%20microtron&rft.jtitle=International%20journal%20of%20radiation%20oncology,%20biology,%20physics&rft.au=Mageras,%20G.S.&rft.date=1994-11-15&rft.volume=30&rft.issue=4&rft.spage=971&rft.epage=978&rft.pages=971-978&rft.issn=0360-3016&rft.eissn=1879-355X&rft.coden=IOBPD3&rft_id=info:doi/10.1016/0360-3016(94)90374-3&rft_dat=%3Cproquest_cross%3E76815248%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76815248&rft_id=info:pmid/7961001&rft_els_id=0360301694903743&rfr_iscdi=true