Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron
Purpose : We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron. Methods and Materials : The microtron is equipped with a multi...
Gespeichert in:
Veröffentlicht in: | International journal of radiation oncology, biology, physics biology, physics, 1994-11, Vol.30 (4), p.971-978 |
---|---|
Hauptverfasser: | , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 978 |
---|---|
container_issue | 4 |
container_start_page | 971 |
container_title | International journal of radiation oncology, biology, physics |
container_volume | 30 |
creator | Mageras, G.S. Fuks, Z. O'Brien, J. Brewster, L.J. Burman, C. Chui, C.S. Leibel, S.A. Ling, C.C. Masterson, M.E. Mohan, R. Kutcher, G.J. |
description | Purpose
: We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron.
Methods and Materials
: The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance.
Results
: Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months.
Conclusion
: Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging. |
doi_str_mv | 10.1016/0360-3016(94)90374-3 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76815248</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0360301694903743</els_id><sourcerecordid>76815248</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</originalsourceid><addsrcrecordid>eNp9kU2P1SAUhonRjHdG_4EmLIzRRfVQSj82Jmbi6CRj3KhxRygcHEwLFag6iT9eeu_NXbriAA8vhwdCnjB4xYC1r4G3UPFSvRialwPwrqn4PbJjfTdUXIhv98nuhDwk5yn9AADGuuaMnHVDy8pkR_5ee5edmqienHe6FPhnwejQa6S_Xb6lOszLmjFWOvgcwzShKWvehjgXOirjQr7FqJY7GiwtJV1iSFllpGty_jtVVED1Eb_SGc3-htnpGEqUf0QeWDUlfHwcL8iXq3efLz9UN5_eX1--vak079tcaRBcDTUgH5UAy4xqTD2OlndWjRpGxWuDYGAUpmeWaVA1A1E3iom2E8j5BXl-yC2d_VwxZTm7pHGalMewJtm1PSt8X8DmAJYGU4po5RLdrOKdZCA36XIzKjejcmjkXrrc8p8e89exPPJ06Gi57D877qtUBNiovHbphHHOGtZvMW8OGBYXvxxGmfT-I4yLqLM0wf2_j38klZ_g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76815248</pqid></control><display><type>article</type><title>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Mageras, G.S. ; Fuks, Z. ; O'Brien, J. ; Brewster, L.J. ; Burman, C. ; Chui, C.S. ; Leibel, S.A. ; Ling, C.C. ; Masterson, M.E. ; Mohan, R. ; Kutcher, G.J.</creator><creatorcontrib>Mageras, G.S. ; Fuks, Z. ; O'Brien, J. ; Brewster, L.J. ; Burman, C. ; Chui, C.S. ; Leibel, S.A. ; Ling, C.C. ; Masterson, M.E. ; Mohan, R. ; Kutcher, G.J.</creatorcontrib><description>Purpose
: We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron.
Methods and Materials
: The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance.
Results
: Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months.
Conclusion
: Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.</description><identifier>ISSN: 0360-3016</identifier><identifier>EISSN: 1879-355X</identifier><identifier>DOI: 10.1016/0360-3016(94)90374-3</identifier><identifier>PMID: 7961001</identifier><identifier>CODEN: IOBPD3</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Computer-controlled therapy ; Conformal radiotherapy ; Diseases of the urinary system ; Humans ; Male ; Medical sciences ; Multileaf collimator ; Prostate ; Prostatic Neoplasms - radiotherapy ; Radiotherapy Dosage ; Radiotherapy, Computer-Assisted - instrumentation ; Radiotherapy, Computer-Assisted - methods ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Reproducibility of Results ; Software</subject><ispartof>International journal of radiation oncology, biology, physics, 1994-11, Vol.30 (4), p.971-978</ispartof><rights>1994</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</citedby><cites>FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0360-3016(94)90374-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>310,311,315,781,785,790,791,3551,23935,23936,25145,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3314183$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7961001$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mageras, G.S.</creatorcontrib><creatorcontrib>Fuks, Z.</creatorcontrib><creatorcontrib>O'Brien, J.</creatorcontrib><creatorcontrib>Brewster, L.J.</creatorcontrib><creatorcontrib>Burman, C.</creatorcontrib><creatorcontrib>Chui, C.S.</creatorcontrib><creatorcontrib>Leibel, S.A.</creatorcontrib><creatorcontrib>Ling, C.C.</creatorcontrib><creatorcontrib>Masterson, M.E.</creatorcontrib><creatorcontrib>Mohan, R.</creatorcontrib><creatorcontrib>Kutcher, G.J.</creatorcontrib><title>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</title><title>International journal of radiation oncology, biology, physics</title><addtitle>Int J Radiat Oncol Biol Phys</addtitle><description>Purpose
: We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron.
Methods and Materials
: The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance.
Results
: Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months.
Conclusion
: Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.</description><subject>Biological and medical sciences</subject><subject>Computer-controlled therapy</subject><subject>Conformal radiotherapy</subject><subject>Diseases of the urinary system</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Multileaf collimator</subject><subject>Prostate</subject><subject>Prostatic Neoplasms - radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy, Computer-Assisted - instrumentation</subject><subject>Radiotherapy, Computer-Assisted - methods</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Reproducibility of Results</subject><subject>Software</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2P1SAUhonRjHdG_4EmLIzRRfVQSj82Jmbi6CRj3KhxRygcHEwLFag6iT9eeu_NXbriAA8vhwdCnjB4xYC1r4G3UPFSvRialwPwrqn4PbJjfTdUXIhv98nuhDwk5yn9AADGuuaMnHVDy8pkR_5ee5edmqienHe6FPhnwejQa6S_Xb6lOszLmjFWOvgcwzShKWvehjgXOirjQr7FqJY7GiwtJV1iSFllpGty_jtVVED1Eb_SGc3-htnpGEqUf0QeWDUlfHwcL8iXq3efLz9UN5_eX1--vak079tcaRBcDTUgH5UAy4xqTD2OlndWjRpGxWuDYGAUpmeWaVA1A1E3iom2E8j5BXl-yC2d_VwxZTm7pHGalMewJtm1PSt8X8DmAJYGU4po5RLdrOKdZCA36XIzKjejcmjkXrrc8p8e89exPPJ06Gi57D877qtUBNiovHbphHHOGtZvMW8OGBYXvxxGmfT-I4yLqLM0wf2_j38klZ_g</recordid><startdate>19941115</startdate><enddate>19941115</enddate><creator>Mageras, G.S.</creator><creator>Fuks, Z.</creator><creator>O'Brien, J.</creator><creator>Brewster, L.J.</creator><creator>Burman, C.</creator><creator>Chui, C.S.</creator><creator>Leibel, S.A.</creator><creator>Ling, C.C.</creator><creator>Masterson, M.E.</creator><creator>Mohan, R.</creator><creator>Kutcher, G.J.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19941115</creationdate><title>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</title><author>Mageras, G.S. ; Fuks, Z. ; O'Brien, J. ; Brewster, L.J. ; Burman, C. ; Chui, C.S. ; Leibel, S.A. ; Ling, C.C. ; Masterson, M.E. ; Mohan, R. ; Kutcher, G.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-c053a920e3ba50f1da4d2bbf37fabc0ba32de0d0b5d81f1c0a210524a15675e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Biological and medical sciences</topic><topic>Computer-controlled therapy</topic><topic>Conformal radiotherapy</topic><topic>Diseases of the urinary system</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Multileaf collimator</topic><topic>Prostate</topic><topic>Prostatic Neoplasms - radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy, Computer-Assisted - instrumentation</topic><topic>Radiotherapy, Computer-Assisted - methods</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Reproducibility of Results</topic><topic>Software</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mageras, G.S.</creatorcontrib><creatorcontrib>Fuks, Z.</creatorcontrib><creatorcontrib>O'Brien, J.</creatorcontrib><creatorcontrib>Brewster, L.J.</creatorcontrib><creatorcontrib>Burman, C.</creatorcontrib><creatorcontrib>Chui, C.S.</creatorcontrib><creatorcontrib>Leibel, S.A.</creatorcontrib><creatorcontrib>Ling, C.C.</creatorcontrib><creatorcontrib>Masterson, M.E.</creatorcontrib><creatorcontrib>Mohan, R.</creatorcontrib><creatorcontrib>Kutcher, G.J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mageras, G.S.</au><au>Fuks, Z.</au><au>O'Brien, J.</au><au>Brewster, L.J.</au><au>Burman, C.</au><au>Chui, C.S.</au><au>Leibel, S.A.</au><au>Ling, C.C.</au><au>Masterson, M.E.</au><au>Mohan, R.</au><au>Kutcher, G.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>1994-11-15</date><risdate>1994</risdate><volume>30</volume><issue>4</issue><spage>971</spage><epage>978</epage><pages>971-978</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><coden>IOBPD3</coden><abstract>Purpose
: We have described previously a model for delivering computer-controlled radiation treatments. We report here on the implementation and first year's clinical experience with such treatments using a 50 MeV medical microtron.
Methods and Materials
: The microtron is equipped with a multileaf collimator and is capable of setting up and treating a sequence of fixed fields called segments, under computer control. An external computer derives machine parameters for the segments from a three-dimensional treatment planning system, transfers them to the microtron control computer, checks the machine settings before allowing dose delivery to begin, and records the treatment. We describe the patient treatment methodology, portal film acquisition, electronic portal imaging, and quality assurance.
Results
: Patient treatments began in July 1992, comprising six-segment conformal treatments of the prostate. Using the recorded treatment data, the system performance has been examined and compared to other treatment machines. The average treatment time is 10 min, of which 4 min is for computer-controlled setup and irradiation; the remaining time is for patient positioning and checking of clearances. Long-term reproducibility of computer-controlled setup of the gantry and multileaf position is better than 0.5° and 1 mm, respectively. Termination due to a machine fault has occurred in 5.5% of treatments, improving to 2.5% in recent months.
Conclusion
: Our initial experience indicates that computer-controlled segmental therapy can be performed reliably on a routine basis. Treatment times with the microtron are significantly shorter than with conventional linacs, and setup accuracy is consistent with that needed for conformal therapy. We believe that treatment times can be further improved through software upgrades and integration of electronic portal imaging.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7961001</pmid><doi>10.1016/0360-3016(94)90374-3</doi><tpages>8</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0360-3016 |
ispartof | International journal of radiation oncology, biology, physics, 1994-11, Vol.30 (4), p.971-978 |
issn | 0360-3016 1879-355X |
language | eng |
recordid | cdi_proquest_miscellaneous_76815248 |
source | MEDLINE; Access via ScienceDirect (Elsevier) |
subjects | Biological and medical sciences Computer-controlled therapy Conformal radiotherapy Diseases of the urinary system Humans Male Medical sciences Multileaf collimator Prostate Prostatic Neoplasms - radiotherapy Radiotherapy Dosage Radiotherapy, Computer-Assisted - instrumentation Radiotherapy, Computer-Assisted - methods Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Reproducibility of Results Software |
title | Initial clinical experience with computer-controlled conformal radiotherapy of the prostate using a 50-MeV medical microtron |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T13%3A11%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Initial%20clinical%20experience%20with%20computer-controlled%20conformal%20radiotherapy%20of%20the%20prostate%20using%20a%2050-MeV%20medical%20microtron&rft.jtitle=International%20journal%20of%20radiation%20oncology,%20biology,%20physics&rft.au=Mageras,%20G.S.&rft.date=1994-11-15&rft.volume=30&rft.issue=4&rft.spage=971&rft.epage=978&rft.pages=971-978&rft.issn=0360-3016&rft.eissn=1879-355X&rft.coden=IOBPD3&rft_id=info:doi/10.1016/0360-3016(94)90374-3&rft_dat=%3Cproquest_cross%3E76815248%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76815248&rft_id=info:pmid/7961001&rft_els_id=0360301694903743&rfr_iscdi=true |